| Presentation | 2016-07-05 A neuromarker of anxiety from whole-brain functional connectivity. Yu Takagi, Yuki Sakai, Saori C. Tanaka, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | There are times when an anxiety drives us to make an effort to achieve our goal and times when it may also harm our daily life. Previous studies have investigated neural substrates of anxiety by inspecting neural activities during a specific task or resting state. However, common neural substrates between task and resting state remain unclear. Here, to investigate “universal” neural substrates of anxiety by data driven procedures, we obtained human subjects’ neural activities by using functional magnetic resonance imaging (fMRI) during subjects saw both of anxious and neutral stimuli. We identified neural markers consisting of patterns of functional connectivity which serve to distinguish anxious states from neutral states. Further, we tried to predict individual’s daily anxiousness by applying the neural markers to the external resting-state fMRI. We show that our whole-brain anxiousness neural marker not only detect the anxious state during task, but also generalized to resting-state. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | fMRI / anxiety / resting-state brain activity / functional connectivity / machine learning |
| Paper # | NC2016-6 |
| Date of Issue | 2016-06-28 (NC) |
| Conference Information | |
| Committee | NC / IPSJ-BIO / IBISML / IPSJ-MPS |
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| Conference Date | 2016/7/4(3days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Okinawa Institute of Science and Technology |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Machine Learning Approach to Biodata Mining, and General |
| Chair | Shigeo Sato(Tohoku Univ.) / / Kenji Fukumizu(ISM) |
| Vice Chair | Masafumi Hagiwara(Keio Univ.) / / Masashi Sugiyama(Univ. of Tokyo) / Hisashi Kashima(Kyoto Univ.) |
| Secretary | Masafumi Hagiwara(Kyoto Sangyo Univ.) / (Tokyo Inst. of Tech.) / Masashi Sugiyama / Hisashi Kashima(Univ. of Tokyo) / (Nagoya Inst. of Tech.) |
| Assistant | Hisanao Akima(Tohoku Univ.) / Yoshihisa Shinozawa(Keio Univ.) / / Toshihiro Kamishima(AIST) / Tomoharu Iwata(NTT) |
| Paper Information | |
| Registration To | Technical Committee on Neurocomputing / Special Interest Group on Bioinformatics and Genomics / Technical Committee on Infomation-Based Induction Sciences and Machine Learning / Special Interest Group on Mathematical Modeling and Problem Solving |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A neuromarker of anxiety from whole-brain functional connectivity. |
| Sub Title (in English) | |
| Keyword(1) | fMRI |
| Keyword(2) | anxiety |
| Keyword(3) | resting-state brain activity |
| Keyword(4) | functional connectivity |
| Keyword(5) | machine learning |
| 1st Author's Name | Yu Takagi |
| 1st Author's Affiliation | Nara Institute of Science and Technology/Advanced Telecommunications Research Institute International(NAIST/ATR) |
| 2nd Author's Name | Yuki Sakai |
| 2nd Author's Affiliation | Kyoto Prefectural University of Medicine/Advanced Telecommunications Research Institute International(Kyoto Pref. Univ. Med./ATR) |
| 3rd Author's Name | Saori C. Tanaka |
| 3rd Author's Affiliation | Advanced Telecommunications Research Institute International(ATR) |
| Date | 2016-07-05 |
| Paper # | NC2016-6 |
| Volume (vol) | vol.116 |
| Number (no) | NC-120 |
| Page | pp.pp.159-164(NC), |
| #Pages | 6 |
| Date of Issue | 2016-06-28 (NC) |