| Presentation | 2016-03-22 Possible role of angiogenesis in transient post-ischemic hyperperfusion in rats Kazuhiro Nakamura, Junko Kawamura, Yasushi Kondoh, Hajime MIyata, Toshibumi Kinoshita, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Post-ischemic hyperperfusion was observed a few days after transient middle cerebral artery occlusion (tMCAO) . We assume the hyperperfusion was caused by angiogenesis occurred after tMCAO. To evaluate the hypothesis, we administrated angiogenesis inhibitor SU5416 and evaluated cerebral blood flow in 48 hours after MCAO with continuous arterial spin labeling in MRI. Post-ischmeic hyperperfusion in caudate nucleus was statistically reduced in SU5416 administration compared to control group. Dilated arteries and vessel endothelial cell proliferation in caudate nucleus was inhibited in pathological preparation. The post-ischemic hyperperfusion might be related to the angiogenesis. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | CBF / MRI / Stroke |
| Paper # | MBE2015-112 |
| Date of Issue | 2016-03-15 (MBE) |
| Conference Information | |
| Committee | MBE / NC |
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| Conference Date | 2016/3/22(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Tamagawa University |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | Tetsuo Kobayashi(Kyoto Univ.) / Toshimichi Saito(Hosei Univ.) |
| Vice Chair | Yutaka Fukuoka(Kogakuin Univ.) / Shigeo Sato(Tohoku Univ.) |
| Secretary | Yutaka Fukuoka(akita noken) / Shigeo Sato(Kogakuin Univ.) |
| Assistant | Takenori Oida(Kyoto Univ.) / Ryota Horie(Shibaura Inst. of Tech.) / Hiroyuki Kanbara(Tokyo Inst. of Tech.) / Hisanao Akima(Tohoku Univ.) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Possible role of angiogenesis in transient post-ischemic hyperperfusion in rats |
| Sub Title (in English) | |
| Keyword(1) | CBF |
| Keyword(2) | MRI |
| Keyword(3) | Stroke |
| 1st Author's Name | Kazuhiro Nakamura |
| 1st Author's Affiliation | Akita Research Institute for Brain and Blood Vessels(Akita Noken) |
| 2nd Author's Name | Junko Kawamura |
| 2nd Author's Affiliation | Akita Research Institute for Brain and Blood Vessels(Akita Noken) |
| 3rd Author's Name | Yasushi Kondoh |
| 3rd Author's Affiliation | Akita Research Institute for Brain and Blood Vessels(Akita Noken) |
| 4th Author's Name | Hajime MIyata |
| 4th Author's Affiliation | Akita Research Institute for Brain and Blood Vessels(Akita Noken) |
| 5th Author's Name | Toshibumi Kinoshita |
| 5th Author's Affiliation | Akita Research Institute for Brain and Blood Vessels(Akita Noken) |
| Date | 2016-03-22 |
| Paper # | MBE2015-112 |
| Volume (vol) | vol.115 |
| Number (no) | MBE-513 |
| Page | pp.pp.51-54(MBE), |
| #Pages | 4 |
| Date of Issue | 2016-03-15 (MBE) |