Presentation 2015-11-10
Segmental Bayesian estimation of neuronal parameters from spike trains
Isao Tokuda, Huu Hoang,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Multi-electrode recording is now a common technique to simultaneously collect neuronal spike data of a population of the neurons in a brain region, and thus allows exploring various underlying functions of the brain. Computational modeling usually emerges when the parameters of interest cannot be directly measured by the experiments. However, the inverse problem of estimating parameters from spike trains is severely ill-posed due to the huge mismatch in the system complexity between the brain and the model, and thus needs a stochastic approach to find most likely solutions among many possible ones. Since the brain typically exhibits complicated dynamics that is difficult for the model to reproduce, the modeling errors are inevitable. In the present thesis, we introduce a novel methodology based on the Bayesian inference framework to overcome that challenging issue. The experimental spike data is fractioned into short time segments and the model parameters are estimated segment by segment in the constraint that the segmental estimates are fluctuated around the neuronal estimates. By relaxing the parameter search, the segmental Bayes has been hypothesized to compensate the modeling errors and thus improve the estimation accuracy. The performance evaluation on experimental data indicated that the segmental Bayes outperforms the conventional Bayes and the minimum error method by minimizing the fitting errors in the feature space. It also had a strong robustness against non-stationarity of the spike data. This work has been collaboration with Dr. Okito Yamashita, Dr. Masa-aki Sato, Dr. Mitsuo Kawato, and Dr. Keisuke Toyama.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Multi-electrode recording / Bayesian Estimation / Parameter Estimation / Segmentation
Paper # CCS2015-63
Date of Issue 2015-11-02 (CCS)

Conference Information
Committee CCS
Conference Date 2015/11/9(2days)
Place (in Japanese) (See Japanese page)
Place (in English) Inamori Foundation Memorial Building, Kyoto Univ.
Topics (in Japanese) (See Japanese page)
Topics (in English) Interaction and Communication, etc.
Chair Hiroo Sekiya(Chiba Univ.)
Vice Chair Yasuhiro Tsubo(Ritsumeikan Univ.) / Naoki Wakamiya(Osaka Univ.)
Secretary Yasuhiro Tsubo(Kagawa National College of Tech.) / Naoki Wakamiya(Kyoto Sangyo Univ.)
Assistant Takayuki Kimura(Nippon Inst. of Tech.) / Song-Ju Kim(NIMS) / Ryo Takahashi(Kyoto Univ.) / Junnosuke Teramae(Osaka Univ.)

Paper Information
Registration To Technical Committee on Complex Communication Sciences
Language ENG-JTITLE
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Segmental Bayesian estimation of neuronal parameters from spike trains
Sub Title (in English)
Keyword(1) Multi-electrode recording
Keyword(2) Bayesian Estimation
Keyword(3) Parameter Estimation
Keyword(4) Segmentation
1st Author's Name Isao Tokuda
1st Author's Affiliation Ritsumeikan University(Ritsumeikan Univ.)
2nd Author's Name Huu Hoang
2nd Author's Affiliation Ritsumeikan University(Ritsumeikan Univ.)
Date 2015-11-10
Paper # CCS2015-63
Volume (vol) vol.115
Number (no) CCS-300
Page pp.pp.99-102(CCS),
#Pages 4
Date of Issue 2015-11-02 (CCS)