Presentation 2015-11-01
A study on the bifurcation analysis of a human atrial myocyte model toward the creation of a biological pacemaker
Yoshiki Ogawa, Shinji Doi,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Biological pacemaker engineering is a strategy to initiate pacemaker activity in non-pacemaking cells,and it is expected as an alternative to electronic pacemaker. Since it is necessary for biological pacemaker engineering to understand the dynamics of various ion channels comprehensively, we use the mathematical cell model. The purpose of this study is to investigate the method to create a biological pacemaker based on bifurcation analysis of human atrial myocyte model. Since variables with different time scale interfere with detailed bifurcation analyses in the atrial myocyte model, in this report, we investigate the effects of ion concentration change on the model dynamics based on the bifurcation analyses of modified models with some intracellular ion concentration fixed.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) atrial myocyte model / bifurcation analysis / biological pacemaker
Paper # NLP2015-122
Date of Issue 2015-10-24 (NLP)

Conference Information
Committee NLP
Conference Date 2015/10/31(2days)
Place (in Japanese) (See Japanese page)
Place (in English) Nobumoto Ohama Memorial Hall
Topics (in Japanese) (See Japanese page)
Topics (in English) Nonlinear Problems, etc.
Chair Kenya Jinno(Nippon Inst. of Tech.)
Vice Chair Naoto Fujisaka(Hiroshima City Univ.)
Secretary Naoto Fujisaka(Tokyo Univ. of Science)
Assistant Hidehiro Nakano(Tokyo City Univ.) / Hiroyuki Asahara(Okayama Univ. of Science)

Paper Information
Registration To Technical Committee on Nonlinear Problems
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) A study on the bifurcation analysis of a human atrial myocyte model toward the creation of a biological pacemaker
Sub Title (in English)
Keyword(1) atrial myocyte model
Keyword(2) bifurcation analysis
Keyword(3) biological pacemaker
1st Author's Name Yoshiki Ogawa
1st Author's Affiliation Kyoto University(Kyoto Univ.)
2nd Author's Name Shinji Doi
2nd Author's Affiliation Kyoto University(Kyoto Univ.)
Date 2015-11-01
Paper # NLP2015-122
Volume (vol) vol.115
Number (no) NLP-284
Page pp.pp.87-92(NLP),
#Pages 6
Date of Issue 2015-10-24 (NLP)