| Presentation | 2015-08-04 A New Dielectric Dispersion Analysis Using Microwave Bio-Microsensor for Minute Droplet of Liposome Suspension with Target Biomolecules by S-Parameter Method Tomoki Yoshikawa, Ziyang Zhang, Kaoru Yamashita, Minoru Noda, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | A microwave bio-microsensor of coplanar waveguide (CPW) interdigital capacitor (IDC) with droplet of about 0.3 µL of liposome suspension with target biomolecules is newly considered and applied for realizing the evaluation of the permittivity of small target droplet by S-parameter method, similar to Dielectric Dispersion Analysis (DDA) by an open-ended coaxial probe method. Finally, we have successfully detected by the IDC microsensor the interaction between the liposome and target protein of carbonic anhydrase from bovine (CAB), which is intrinsically the same as that observed by the conventional open-ended method. It is significantly important that the IDC method improves the sensitivity, defined as (Δεr/εr)/(solution volume), by about 300 times from the conventional method. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | interdigital capacitor / protein / liposome / interaction / Dielectric Dispersion Analysis (DDA) / S-parameter method / dielectric relaxation width (Δεr) |
| Paper # | ED2015-50 |
| Date of Issue | 2015-07-27 (ED) |
| Conference Information | |
| Committee | ED |
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| Conference Date | 2015/8/3(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Kikai-Shinko-Kaikan Bldg. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Sensor device, MEMS, etc |
| Chair | Koichi Maezawa(Univ. of Toyama) |
| Vice Chair | Kunio Tsuda(Toshiba) |
| Secretary | Kunio Tsuda(NEC) |
| Assistant | Manabu Arai(New JRC) / Masataka Higashiwaki(NICT) |
| Paper Information | |
| Registration To | Technical Committee on Electron Device |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | A New Dielectric Dispersion Analysis Using Microwave Bio-Microsensor for Minute Droplet of Liposome Suspension with Target Biomolecules by S-Parameter Method |
| Sub Title (in English) | |
| Keyword(1) | interdigital capacitor |
| Keyword(2) | protein |
| Keyword(3) | liposome |
| Keyword(4) | interaction |
| Keyword(5) | Dielectric Dispersion Analysis (DDA) |
| Keyword(6) | S-parameter method |
| Keyword(7) | dielectric relaxation width (Δεr) |
| 1st Author's Name | Tomoki Yoshikawa |
| 1st Author's Affiliation | Kyoto Institute of Technology(Kyoto Inst. of Tech.) |
| 2nd Author's Name | Ziyang Zhang |
| 2nd Author's Affiliation | Kyoto Institute of Technology(Kyoto Inst. of Tech.) |
| 3rd Author's Name | Kaoru Yamashita |
| 3rd Author's Affiliation | Kyoto Institute of Technology(Kyoto Inst. of Tech.) |
| 4th Author's Name | Minoru Noda |
| 4th Author's Affiliation | Kyoto Institute of Technology(Kyoto Inst. of Tech.) |
| Date | 2015-08-04 |
| Paper # | ED2015-50 |
| Volume (vol) | vol.115 |
| Number (no) | ED-170 |
| Page | pp.pp.33-36(ED), |
| #Pages | 4 |
| Date of Issue | 2015-07-27 (ED) |