Presentation 2023-03-13
Modulation effects on in vivo neural activity induced by near-infrared ray stimulation to the mouse inferior colliculus
Hiromu Sato, Takashi Tateno,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) In recent years, more attention has been received to infrared neural stimulation (INS) which can modulate the activity of neural tissue through near-infrared light irradiation mainly owing to temperature changes. The inferior colliculus (IC) is one of the potential targets to treat auditory diseases and apply artificial hearing devices because it is one of the crucial relay nuclei where all auditory pathways converge during sound processing. However, there have been no previous reports of INS-induced modulation of neural activity in the IC. In this study, a mathematical model of brain tissue was first simulated, temperature distributions were numerically calculated, and stimulus parameters were selected from the simulation result. Subsequently, INS was administered to the IC of anesthetized mice, and the modulation effect on neural activity was measured using an electrophysiological method. On the basis of the results, we discuss how INS was effectively applied to neuromodulation.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Neural modulation / Brain stimulation / Near-infrared ray / Photothermal effects / Inferior colliculus
Paper # NC2022-94
Date of Issue 2023-03-06 (NC)

Conference Information
Committee NC / MBE
Conference Date 2023/3/13(3days)
Place (in Japanese) (See Japanese page)
Place (in English) The Univ. of Electro-Communications
Topics (in Japanese) (See Japanese page)
Topics (in English) Brain architecture, General
Chair Hiroshi Yamakawa(Univ of Tokyo) / Junichi Hori(Niigata Univ.)
Vice Chair Hirokazu Tanaka(Tokyo City Univ.) / Hisashi Yoshida(Kinki Univ.)
Secretary Hirokazu Tanaka(NTT) / Hisashi Yoshida(NICT)
Assistant Yoshimasa Tawatsuji(Waseda Univ.) / Tomoki Kurikawa(KMU) / Emi Yuda(Tohoku Univ) / Miki Kaneko(Osaka Univ.)

Paper Information
Registration To Technical Committee on Neurocomputing / Technical Committee on ME and Bio Cybernetics
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Modulation effects on in vivo neural activity induced by near-infrared ray stimulation to the mouse inferior colliculus
Sub Title (in English)
Keyword(1) Neural modulation
Keyword(2) Brain stimulation
Keyword(3) Near-infrared ray
Keyword(4) Photothermal effects
Keyword(5) Inferior colliculus
1st Author's Name Hiromu Sato
1st Author's Affiliation Hokkaido University(Hokudai)
2nd Author's Name Takashi Tateno
2nd Author's Affiliation Hokkaido University(Hokudai)
Date 2023-03-13
Paper # NC2022-94
Volume (vol) vol.122
Number (no) NC-425
Page pp.pp.19-24(NC),
#Pages 6
Date of Issue 2023-03-06 (NC)