Presentation 2022-05-19
Simplified physico-mathematical model for low invasive cancer treatment by microbubble-enhanced high-intensity-focused-ultrasound
Shunsuke Kagami, Tetsuya Kanagawa,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Weakly nonlinear propagation of focused ultrasound in the liquid containing many spherical bubbles is theoretically investigated for a low invasive cancer treatment by HIFU. The KZK equation, which has been widely used as the simplified physico-mathematical model for HIFU propagation in pure liquid, is extended that for bubbly liquids by utilizing the volume-averaged basic equations based on two-fluid model for bubbly liquids. The resultant KZK equation consistently describes the nonlinear propagation of focused ultrasound, the nonlinear oscillation of bubbles, the thermal conduction and the temperature fluctuation of gas inside bubbles. Moreover, the numerical calculation utilizing the resultant KZK equation is carried out and moderate temperature rise for applications of cancer treatment by HIFU are obtained.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Bubbly liquid / HIFU / Weakly nonlinear wave / KZK equation / Thermal conduction
Paper # US2022-5
Date of Issue 2022-05-12 (US)

Conference Information
Committee US
Conference Date 2022/5/19(1days)
Place (in Japanese) (See Japanese page)
Place (in English) Kikai-Shinko-Kaikan Bldg.
Topics (in Japanese) (See Japanese page)
Topics (in English) Nonlinear acoustics, Ultrasonics, etc.
Chair Yoshikazu Koike(Shibaura Inst. of Tech.)
Vice Chair Hikaru Miura(Nihon Univ.) / Kentaro Nakamura(Tokyo Inst. of Tech.)
Secretary Hikaru Miura(Tohoku Univ.) / Kentaro Nakamura(Chiba Univ.)
Assistant Shin Yoshizawa(Tohoku Univ.)

Paper Information
Registration To Technical Committee on Ultrasonics
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Simplified physico-mathematical model for low invasive cancer treatment by microbubble-enhanced high-intensity-focused-ultrasound
Sub Title (in English)
Keyword(1) Bubbly liquid
Keyword(2) HIFU
Keyword(3) Weakly nonlinear wave
Keyword(4) KZK equation
Keyword(5) Thermal conduction
1st Author's Name Shunsuke Kagami
1st Author's Affiliation University of Tsukuba(Univ. Tsukuba)
2nd Author's Name Tetsuya Kanagawa
2nd Author's Affiliation University of Tsukuba(Univ. Tsukuba)
Date 2022-05-19
Paper # US2022-5
Volume (vol) vol.122
Number (no) US-36
Page pp.pp.16-20(US),
#Pages 5
Date of Issue 2022-05-12 (US)