| Presentation | 2021-10-28 Neural Mechanisms of Prepulse Inhibition in Drosophila Larvae Kotaro Furuya, Yuki Katsumata, Masayuki Ishibashi, Takako Morimoto, Toru Aonishi, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Prepulse inhibition (PPI) is a phenomenon in which the startle response to stimuli is suppressed by preceding stimuli. In this work, we investigated neural mechanisms underlying PPI in Drosophila larvae using numerical simulation. We confirmed that the neural circuit model of Drosophila larvae proposed by Jovanic et al. can reproduce several experimental results including PPI using the same model and parameters by adjusting the parameters heuristically determined by them. By examining the activity of each neuron during PPI in our model, we identified the neurons contributing to PPI and suggested its neural circuit mechanisms. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Prepulse Inhibition / Drosophila larvae / Neural circuit model / Computational model |
| Paper # | NC2021-18 |
| Date of Issue | 2021-10-21 (NC) |
| Conference Information | |
| Committee | MBE / NC |
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| Conference Date | 2021/10/28(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Online |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | Ryuhei Okuno(Setsunan Univ.) / Rieko Osu(Waseda Univ.) |
| Vice Chair | Junichi Hori(Niigata Univ.) / Hiroshi Yamakawa(Univ of Tokyo) |
| Secretary | Junichi Hori(Osaka Electro-Communication Univ) / Hiroshi Yamakawa(ATR) |
| Assistant | Jun Akazawa(Meiji Univ. of Integrative Medicine) / Emi Yuda(Tohoku Univ) / Nobuhiko Wagatsuma(Toho Univ.) / Tomoki Kurikawa(KMU) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Neural Mechanisms of Prepulse Inhibition in Drosophila Larvae |
| Sub Title (in English) | |
| Keyword(1) | Prepulse Inhibition |
| Keyword(2) | Drosophila larvae |
| Keyword(3) | Neural circuit model |
| Keyword(4) | Computational model |
| 1st Author's Name | Kotaro Furuya |
| 1st Author's Affiliation | Tokyo Institute of Technology(Tokyo Tech) |
| 2nd Author's Name | Yuki Katsumata |
| 2nd Author's Affiliation | Tokyo Institute of Technology(Tokyo Tech) |
| 3rd Author's Name | Masayuki Ishibashi |
| 3rd Author's Affiliation | Tokyo Institute of Technology(Tokyo Tech) |
| 4th Author's Name | Takako Morimoto |
| 4th Author's Affiliation | Tokyo University of Pharmacy and Life Science(TUPLS) |
| 5th Author's Name | Toru Aonishi |
| 5th Author's Affiliation | Tokyo Institute of Technology(Tokyo Tech) |
| Date | 2021-10-28 |
| Paper # | NC2021-18 |
| Volume (vol) | vol.121 |
| Number (no) | NC-223 |
| Page | pp.pp.1-6(NC), |
| #Pages | 6 |
| Date of Issue | 2021-10-21 (NC) |