| Presentation | 2021-03-03 Influence of vestibular neurectomy on the velocity storage mechanism predicted by the neural network model of the optokinetic response faithfully reflecting the cerebellum-brainstem connectome. Yusuke Shinji, Yutaka Hirata, |
|---|---|
| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Most vertebrates has a reflexive eye movement called the optokinetic response (OKR) in response to large visual field motion. OKR stabilizes our vision by following the visual motion to minimize retinal slip. After being given a visual stimulus that periodically switches the direction for a long time, the goldfish acquires a predictable OKR (pOKR) that predicts the switching timing. It has been shown that pOKR requires a neural mechanism formed in the brain stem called the cerebellum and velocity accumulation mechanism (VSM) which is closely related to motion sickness, disembarkation disease, and spatial disorientation. We constructed an OKR model by the artificial neural circuit based on the connectome of the cerebellum and brain stem, which are known anatomically and physiologically. It has been known that the duration of optokinetic nystagmus (OKAN), which reflects the volume of VSM, is significantly shortened by the vestibular nerve incision, but its neural mechanism is unknown. In this study, we perform a vestibular nerve resection simulation using the OKR model by the artificial neural circuit and show the mechanism of shortening the OKAN duration. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Velocity storage mechanism / Vestibular nuclei / Cerebellum / Semicircular Canal / VIII nerve |
| Paper # | NC2020-44 |
| Date of Issue | 2021-02-24 (NC) |
| Conference Information | |
| Committee | NC / MBE |
|---|---|
| Conference Date | 2021/3/3(3days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Online |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Neuro Computing, Medical Engineering, etc. |
| Chair | Kazuyuki Samejima(Tamagawa Univ) / Takashi Watanabe(Tohoku Univ.) |
| Vice Chair | Rieko Osu(Waseda Univ.) / Ryuhei Okuno(Setsunan Univ.) |
| Secretary | Rieko Osu(NTT) / Ryuhei Okuno(ATR) |
| Assistant | Ken Takiyama(TUAT) / Nobuhiko Wagatsuma(Toho Univ.) / Akihiro Karashima(Tohoku Inst. of Tech.) / Jun Akazawa(Meiji Univ. of Integrative Medicine) |
| Paper Information | |
| Registration To | Technical Committee on Neurocomputing / Technical Committee on ME and Bio Cybernetics |
|---|---|
| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Influence of vestibular neurectomy on the velocity storage mechanism predicted by the neural network model of the optokinetic response faithfully reflecting the cerebellum-brainstem connectome. |
| Sub Title (in English) | |
| Keyword(1) | Velocity storage mechanism |
| Keyword(2) | Vestibular nuclei |
| Keyword(3) | Cerebellum |
| Keyword(4) | Semicircular Canal |
| Keyword(5) | VIII nerve |
| 1st Author's Name | Yusuke Shinji |
| 1st Author's Affiliation | Chubu University(Chubu Univ.) |
| 2nd Author's Name | Yutaka Hirata |
| 2nd Author's Affiliation | Chubu University(Chubu Univ.) |
| Date | 2021-03-03 |
| Paper # | NC2020-44 |
| Volume (vol) | vol.120 |
| Number (no) | NC-403 |
| Page | pp.pp.12-16(NC), |
| #Pages | 5 |
| Date of Issue | 2021-02-24 (NC) |