Presentation 2021-02-19
Development and application of a highly sensitive color vision system
Masatoshi Kitaguchi, Sayumi Tsuyuguchi, Miwa Hashizume, Ayuka Kato, Tomoyuki Naito, Hiromichi Sato,
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Abstract(in Japanese) (See Japanese page)
Abstract(in English) Dystrophinopathy is a progressive intractable disease that is caused by an abnormality in the gene for the causative protein dystrophin, leads to degeneration and necrosis of skeletal muscle, and is known to also occur in the retina and brain. However, no systematic method has been established to examine the progress and extent of the disease over time. Painful and invasive methods, such as skeletal muscle biopsy, are used to examine the status of the disease in individual cases and are particularly distressing for patients who develop the disease at an early age, such as 2 or 3 years old. In this study, we focused on the abnormalities of red?green color vision based on patients’ paintings in previous studies and developed a simple color vision test system that can be used in the supine and prone positions on a bed. The results showed an association between the dystrophin gene isoform mutations that trigger the disease and a decrease in sensitivity to both red and green based on a tendency toward visual sensitivity to both luminance and hue. This suggests the possibility of monitoring the progress of the disease using a simple, non-invasive color vision test.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) color blindness test / dystrophinopathy / retina / cone / luminance / isofome / gene
Paper # HIP2020-91
Date of Issue 2021-02-11 (HIP)

Conference Information
Committee HIP / VRSJ
Conference Date 2021/2/18(2days)
Place (in Japanese) (See Japanese page)
Place (in English) Online
Topics (in Japanese) (See Japanese page)
Topics (in English)
Chair Shuichi Sakamoto(Tohoku Univ.)
Vice Chair Yuji Wada(Ritsumeikan Univ.) / Sachiko Kiyokawa(Nagoya Univ.)
Secretary Yuji Wada(NICT) / Sachiko Kiyokawa(NTT) / (NICT)
Assistant Hidetoshi Kanaya(Ritsumeikan Univ.) / Yuki Yamada(Kyushu Univ.)

Paper Information
Registration To Technical Committee on Human Information Processing / The Virtual Reality Society of Japan
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Development and application of a highly sensitive color vision system
Sub Title (in English)
Keyword(1) color blindness test
Keyword(2) dystrophinopathy
Keyword(3) retina
Keyword(4) cone
Keyword(5) luminance
Keyword(6) isofome
Keyword(7) gene
1st Author's Name Masatoshi Kitaguchi
1st Author's Affiliation Osaka University(Osaka Univ.)
2nd Author's Name Sayumi Tsuyuguchi
2nd Author's Affiliation Osaka University(Osaka Univ.)
3rd Author's Name Miwa Hashizume
3rd Author's Affiliation Osaka University(Osaka Univ.)
4th Author's Name Ayuka Kato
4th Author's Affiliation Osaka University(Osaka Univ.)
5th Author's Name Tomoyuki Naito
5th Author's Affiliation Osaka University(Osaka Univ.)
6th Author's Name Hiromichi Sato
6th Author's Affiliation Osaka University(Osaka Univ.)
Date 2021-02-19
Paper # HIP2020-91
Volume (vol) vol.120
Number (no) HIP-375
Page pp.pp.78-83(HIP),
#Pages 6
Date of Issue 2021-02-11 (HIP)