| Presentation | 2021-01-22 The different patterns of epileptic discharges in rat hippocampal slices based on the frequency of high frequency oscillations Toyohiro Sawada, Hirofumi Arai, Ryusei Maeda, Kiyohisa Natume, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | Electroencephalogram (EEG) reflects brain states and is classified by kinds of frequency. Among them, ripple or high frequency oscillations (HFO) in the 100 Hz~500 Hz range can be recorded from healthy brain and also from pathological brain, for example from hippocampus. HFO can be a biomarker of epileptogenesis. In this study, we revealed that there were three kinds of epileptic discharges interictal (IID), preictal (PID) and ictal discharges (ID) with the application of proepileptic agents to rat hippocampal slices. The three patterns had different HFO frequencies and durations. Furthermore, in CA3 mini slice, IID and PID were induced, and ID could not be observed. These results suggest that IID and PID may be induced in the local network in CA3, and ID is induced in the global network in CA3, CA1, and DG. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Epilepsy / Hippocampus / High frequency oscillations |
| Paper # | NLP2020-54 |
| Date of Issue | 2021-01-14 (NLP) |
| Conference Information | |
| Committee | NC / NLP |
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| Conference Date | 2021/1/21(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Online |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | NC，NLP |
| Chair | Kazuyuki Samejima(Tamagawa Univ) / Kiyohisa Natsume(Kyushu Inst. of Tech.) |
| Vice Chair | Rieko Osu(Waseda Univ.) / Takuji Kosaka(Chukyo Univ.) |
| Secretary | Rieko Osu(NTT) / Takuji Kosaka(ATR) |
| Assistant | Ken Takiyama(TUAT) / Nobuhiko Wagatsuma(Toho Univ.) / Toshikaza Samura(Yamaguchi Univ.) / Hideyuki Kato(Oita Univ.) |
| Paper Information | |
| Registration To | Technical Committee on Neurocomputing / Technical Committee on Nonlinear Problems |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | The different patterns of epileptic discharges in rat hippocampal slices based on the frequency of high frequency oscillations |
| Sub Title (in English) | |
| Keyword(1) | Epilepsy |
| Keyword(2) | Hippocampus |
| Keyword(3) | High frequency oscillations |
| 1st Author's Name | Toyohiro Sawada |
| 1st Author's Affiliation | Kyushu Institute of Technology(KIT) |
| 2nd Author's Name | Hirofumi Arai |
| 2nd Author's Affiliation | Kyushu Institute of Technology(KIT) |
| 3rd Author's Name | Ryusei Maeda |
| 3rd Author's Affiliation | Kyushu Institute of Technology(KIT) |
| 4th Author's Name | Kiyohisa Natume |
| 4th Author's Affiliation | Kyushu Institute of Technology(KIT) |
| Date | 2021-01-22 |
| Paper # | NLP2020-54 |
| Volume (vol) | vol.120 |
| Number (no) | NLP-330 |
| Page | pp.pp.76-81(NLP), |
| #Pages | 6 |
| Date of Issue | 2021-01-14 (NLP) |