| Presentation | 2020-12-14 The physiological protocol of temporary BBB opening by High Intensity Ultrasound Kazuhide Okada, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In case of one of serious brain tumour, glioblastoma whose cure rate is pretty low, the promising therapy is to pass the anti-tumour drug from blood side to the brain side, by irradiating ultrasound to BBB attached with the blood vessel in which microbubbles are filled by the intravenous injection prior to its therapy, to open TJ (tight junction) of BBB. But BBB is the important path which transmit the lactate and the amino acid to the whole body. So it must be closed as soon as the said drug cross BBB. So, In this study how to open/ close BBB physically and concretely is discussed. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | glicoma / glioblastoma / HIFU / BBB / Tight Junction / microbubble / intravenous injection |
| Paper # | US2020-55 |
| Date of Issue | 2020-12-07 (US) |
| Conference Information | |
| Committee | US |
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| Conference Date | 2020/12/14(1days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Online |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Chair | Hikaru Miura(Nihon Univ.) |
| Vice Chair | Jun Kondo(Shizuoka Univ.) / Yoshikazu Koike(Shibaura Inst. of Tech.) |
| Secretary | Jun Kondo(Doshisha Univ.) / Yoshikazu Koike(Tohoku Univ.) |
| Assistant | Shinnosuke Hirata(Tokyo Inst. of Tech.) |
| Paper Information | |
| Registration To | Technical Committee on Ultrasonics |
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| Language | ENG-JTITLE |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | The physiological protocol of temporary BBB opening by High Intensity Ultrasound |
| Sub Title (in English) | To deliver the anti-cancer drug to the affected area of glioblastoma smoothly |
| Keyword(1) | glicoma |
| Keyword(2) | glioblastoma |
| Keyword(3) | HIFU |
| Keyword(4) | BBB |
| Keyword(5) | Tight Junction |
| Keyword(6) | microbubble |
| Keyword(7) | intravenous injection |
| 1st Author's Name | Kazuhide Okada |
| 1st Author's Affiliation | New Tokyo Medical College(NTMC) |
| Date | 2020-12-14 |
| Paper # | US2020-55 |
| Volume (vol) | vol.120 |
| Number (no) | US-295 |
| Page | pp.pp.28-33(US), |
| #Pages | 6 |
| Date of Issue | 2020-12-07 (US) |