| Presentation | 2020-10-29 Correction methods of blood volume change-derived noise in flavoprotein fluorescence imaging in vivo Shunya Okano, Ryunosuke Togawa, Kentaro Oka, Mitsuyuki Nakao, Norihiro Katayama, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | The flavoprotein autofluorescence imaging (FAI) is a functional optical imaging method of the brain that utilizes the green autofluorescence change associated with its metabolic level. This method allows label-free and long-term measurement of brain function. However, the in vivo FAI data contain significant noise due to fluctuations in blood volume change. To solve this problem, several methods have been proposed to correct the fluorescence signal. In this study, we propose a novel correction method based on the modified Lambert-Beer law. The proposed method provides a finer brain map responding to visual stimuli than conventional methods. This result suggests that the proposed method has a better correction ability than the conventional method. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | flavoprotein autofluorescence imaging / hemodynamics / neurovascular coupling / functional brain imaging / optical imaging / brain / metabolism |
| Paper # | MBE2020-13 |
| Date of Issue | 2020-10-22 (MBE) |
| Conference Information | |
| Committee | MBE / NC / NLP / CAS |
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| Conference Date | 2020/10/29(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Online |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | ME，NC，CAS，NLP |
| Chair | Takashi Watanabe(Tohoku Univ.) / Kazuyuki Samejima(Tamagawa Univ) / Kiyohisa Natsume(Kyushu Inst. of Tech.) / Yasuhiro Takashima(Univ. of Kitakyushu) |
| Vice Chair | Ryuhei Okuno(Setsunan Univ.) / Rieko Osu(Waseda Univ.) / Takuji Kosaka(Chukyo Univ.) / Hiroki Sato(Sony LSI Design) |
| Secretary | Ryuhei Okuno(Akita-noken) / Rieko Osu(NTT) / Takuji Kosaka(ATR) / Hiroki Sato(Kyushu Inst. of Tech.) |
| Assistant | Akihiro Karashima(Tohoku Inst. of Tech.) / Jun Akazawa(Meiji Univ. of Integrative Medicine) / Ken Takiyama(TUAT) / Nobuhiko Wagatsuma(Toho Univ.) / Toshikaza Samura(Yamaguchi Univ.) / Hideyuki Kato(Oita Univ.) / Motoi Yamaguchi(TECHNOPRO) / Yohei Nakamura(Hitachi) |
| Paper Information | |
| Registration To | Technical Committee on ME and Bio Cybernetics / Technical Committee on Neurocomputing / Technical Committee on Nonlinear Problems / Technical Committee on Circuits and Systems |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Correction methods of blood volume change-derived noise in flavoprotein fluorescence imaging in vivo |
| Sub Title (in English) | |
| Keyword(1) | flavoprotein autofluorescence imaging |
| Keyword(2) | hemodynamics |
| Keyword(3) | neurovascular coupling |
| Keyword(4) | functional brain imaging |
| Keyword(5) | optical imaging |
| Keyword(6) | brain |
| Keyword(7) | metabolism |
| 1st Author's Name | Shunya Okano |
| 1st Author's Affiliation | Tohoku University(Tohoku Univ) |
| 2nd Author's Name | Ryunosuke Togawa |
| 2nd Author's Affiliation | Tohoku University(Tohoku Univ) |
| 3rd Author's Name | Kentaro Oka |
| 3rd Author's Affiliation | Tohoku University(Tohoku Univ) |
| 4th Author's Name | Mitsuyuki Nakao |
| 4th Author's Affiliation | Tohoku University(Tohoku Univ) |
| 5th Author's Name | Norihiro Katayama |
| 5th Author's Affiliation | Tohoku University(Tohoku Univ) |
| Date | 2020-10-29 |
| Paper # | MBE2020-13 |
| Volume (vol) | vol.120 |
| Number (no) | MBE-215 |
| Page | pp.pp.5-8(MBE), |
| #Pages | 4 |
| Date of Issue | 2020-10-22 (MBE) |