| Presentation | 2020-01-30 Construction of Basis Vectors for Representation of Immunostaining Combination by Non-negative Matrix Decomposition Kaho Ko, Noriaki Hashimoto, Tatsuya Yokota, Masato Nakaguro, Kei Kohno, Shigeo Nakamura, Ichiro Takeuchi, Hidekata Hontani, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | In this paper, we propose a method that constructs a set of basis vectors for representing combination of immunostaining used to diagnose malignant lymphoma with fewer parameters by means of constrained non-negative matrix factorization. Immunostaining combinations can be represented by binary matrices, of which operations are Boolean, and it is known that matrix decomposition with Boolean operation is NP-hard. We hence relax this problem to a constrained non-negative real matrix decomposition and solve the relaxed problem using an ADMM (Alternating Direction Method of Multipliers). In addition, we introduce an L1-regularization technique to make the method stable against stains infrequently used. We show the concrete algorithms and demonstrate the experimental results that show the performance of the proposed method. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Non-negative matrix decomposition / Boolean Matrix Factorization / Text analysis |
| Paper # | MI2019-99 |
| Date of Issue | 2020-01-22 (MI) |
| Conference Information | |
| Committee | MI |
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| Conference Date | 2020/1/29(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | OKINAWAKEN SEINENKAIKAN |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Medical Image Engineering, Analysis, Recognition, etc. |
| Chair | Yoshiki Kawata(Tokushima Univ.) |
| Vice Chair | Takayuki Kitasaka(Aichi Inst. of Tech.) / Hidekata Hontani(Nagoya Inst. of Tech.) |
| Secretary | Takayuki Kitasaka(Yamaguchi Univ.) / Hidekata Hontani(Univ. of Hyogo) |
| Assistant | Hotaka Takizawa(Tsukuba Univ.) / Yoshito Otake(NAIST) |
| Paper Information | |
| Registration To | Technical Committee on Medical Imaging |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Construction of Basis Vectors for Representation of Immunostaining Combination by Non-negative Matrix Decomposition |
| Sub Title (in English) | |
| Keyword(1) | Non-negative matrix decomposition |
| Keyword(2) | Boolean Matrix Factorization |
| Keyword(3) | Text analysis |
| 1st Author's Name | Kaho Ko |
| 1st Author's Affiliation | Nagoya Institute of Technology(NITech) |
| 2nd Author's Name | Noriaki Hashimoto |
| 2nd Author's Affiliation | Nagoya Institute of Technology(NITech) |
| 3rd Author's Name | Tatsuya Yokota |
| 3rd Author's Affiliation | Nagoya Institute of Technology(NITech) |
| 4th Author's Name | Masato Nakaguro |
| 4th Author's Affiliation | Nagoya University Hospital(NUH) |
| 5th Author's Name | Kei Kohno |
| 5th Author's Affiliation | Nagoya University Hospital(NUH) |
| 6th Author's Name | Shigeo Nakamura |
| 6th Author's Affiliation | Nagoya University Hospital(NUH) |
| 7th Author's Name | Ichiro Takeuchi |
| 7th Author's Affiliation | Nagoya Institute of Technology(NITech) |
| 8th Author's Name | Hidekata Hontani |
| 8th Author's Affiliation | Nagoya Institute of Technology(NITech) |
| Date | 2020-01-30 |
| Paper # | MI2019-99 |
| Volume (vol) | vol.119 |
| Number (no) | MI-399 |
| Page | pp.pp.151-154(MI), |
| #Pages | 4 |
| Date of Issue | 2020-01-22 (MI) |