Presentation 2019-09-04
Domain-adversarial multiple instance learning for subtype classification of malignant lymphoma
Daisuke Fukushima, Ryoichi Koga, Noriaki Hashimoto, Kaho Ko, Masato Nakaguro, Kei Kohno, Shigeo Nakamura, Hidekata Hontani, Ichiro Takeuchi,
PDF Download Page PDF download Page Link
Abstract(in Japanese) (See Japanese page)
Abstract(in English) We classify subtypes of malignant lymphoma using convolutional neural network with digital pathological images as input for computer-aided diagnosis. Generally, when the input image is large, the patch image is extracted from the entire sample. However, when we have no information for tumor regions in the sample, it is difficult that correct labels are apprppriately given to each patch image. We address such a problem using multiple instance learning. In addition, it is known that the variety of staining condition of the input pathological image affects the performance of image analysis. We confirmed that the classification accuracy was improved using domain-adversarial learning.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) pathological image / malignant lymphoma / onvolutional neural network / multiple instance learning / domain-adversarial learning
Paper # PRMU2019-15,MI2019-34
Date of Issue 2019-08-28 (PRMU, MI)

Conference Information
Committee PRMU / MI / IPSJ-CVIM
Conference Date 2019/9/4(2days)
Place (in Japanese) (See Japanese page)
Place (in English)
Topics (in Japanese) (See Japanese page)
Topics (in English)
Chair Yoichi Sato(Univ. of Tokyo) / Yoshiki Kawata(Tokushima Univ.)
Vice Chair Toru Tamaki(Hiroshima Univ.) / Akisato Kimura(NTT) / Takayuki Kitasaka(Aichi Inst. of Tech.) / Hidekata Hontani(Nagoya Inst. of Tech.)
Secretary Toru Tamaki(NTT) / Akisato Kimura(OMRON SINICX) / Takayuki Kitasaka(Yamaguchi Univ.) / Hidekata Hontani(Univ. of Hyogo)
Assistant Yusuke Uchida(DeNA) / Takayoshi Yamashita(Chubu Univ.) / Hotaka Takizawa(Tsukuba Univ.) / Yoshito Otake(NAIST)

Paper Information
Registration To Technical Committee on Pattern Recognition and Media Understanding / Technical Committee on Medical Imaging / Special Interest Group on Computer Vision and Image Media
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) Domain-adversarial multiple instance learning for subtype classification of malignant lymphoma
Sub Title (in English)
Keyword(1) pathological image
Keyword(2) malignant lymphoma
Keyword(3) onvolutional neural network
Keyword(4) multiple instance learning
Keyword(5) domain-adversarial learning
1st Author's Name Daisuke Fukushima
1st Author's Affiliation Nagoya Institute of Technology(Nagoya Inst. of Tech)
2nd Author's Name Ryoichi Koga
2nd Author's Affiliation Nagoya Institute of Technology(Nagoya Inst. of Tech)
3rd Author's Name Noriaki Hashimoto
3rd Author's Affiliation Nagoya Institute of Technology(Nagoya Inst. of Tech)
4th Author's Name Kaho Ko
4th Author's Affiliation Nagoya Institute of Technology(Nagoya Inst. of Tech)
5th Author's Name Masato Nakaguro
5th Author's Affiliation Nagoya University Hospital(Nagoya Univ. Hospital)
6th Author's Name Kei Kohno
6th Author's Affiliation Nagoya University Hospital(Nagoya Univ. Hospital)
7th Author's Name Shigeo Nakamura
7th Author's Affiliation Nagoya University Hospital(Nagoya Univ. Hospital)
8th Author's Name Hidekata Hontani
8th Author's Affiliation Nagoya Institute of Technology(Nagoya Inst of Tech)
9th Author's Name Ichiro Takeuchi
9th Author's Affiliation Nagoya Institute of Technology/RIKEN/National Institute for Materials Science(Nagoya Inst. of Tech/RIKEN/NIMS)
Date 2019-09-04
Paper # PRMU2019-15,MI2019-34
Volume (vol) vol.119
Number (no) PRMU-192,MI-193
Page pp.pp.19-24(PRMU), pp.19-24(MI),
#Pages 6
Date of Issue 2019-08-28 (PRMU, MI)