Presentation 2019-06-18
A sleep state analysis from calcium imaging data using non-negative matrix factorization
Mizuo Nagayama, Toshimitsu Aritake, Hideitsu Hino, Takeshi Kanda, Takehiro Miyazaki, Masashi Yanagisawa, Shotaro Akaho, Noboru Murata,
PDF Download Page PDF download Page Link
Abstract(in Japanese) (See Japanese page)
Abstract(in English) Sleep is an essential process for the survival of animals, however, its phenomenon is poorly understood. We aim to discover phenomena which characterize sleep/wake states from calcium imaging data. Calcium imaging is a technique that can observe activities of a large number of neurons simultaneously, however, it has a disadvantage of low time resolution. Therefore, we do not inference on neuronal activity at a single spike level. In this paper, we made an assumption that groups of neurons become active simultaneously. We used non-negative matrix factorization (NMF) to identify those groups and their neuronal activities in time. As a result, a neuronal group that become active in NREM sleep was estimated.
Keyword(in Japanese) (See Japanese page)
Keyword(in English) Sleep / Calcium Imaging / Non-negative Matrix Factorization
Paper # NC2019-14,IBISML2019-12
Date of Issue 2019-06-10 (NC, IBISML)

Conference Information
Committee NC / IBISML / IPSJ-MPS / IPSJ-BIO
Conference Date 2019/6/17(3days)
Place (in Japanese) (See Japanese page)
Place (in English) Okinawa Institute of Science and Technology
Topics (in Japanese) (See Japanese page)
Topics (in English) Neurocomputing, Machine Learning Approach to Biodata Mining, and General
Chair Hayaru Shouno(UEC) / Hisashi Kashima(Kyoto Univ.) / Masakazu Sekijima(Tokyo Tech) / Hiroyuki Kurata(Kyutech)
Vice Chair Kazuyuki Samejima(Tamagawa Univ) / Masashi Sugiyama(Univ. of Tokyo) / Koji Tsuda(Univ. of Tokyo)
Secretary Kazuyuki Samejima(NAIST) / Masashi Sugiyama(NTT) / Koji Tsuda(Nagoya Inst. of Tech.) / (AIST) / (Nagoya Univ.)
Assistant Takashi Shinozaki(NICT) / Ken Takiyama(TUAT) / Tomoharu Iwata(NTT) / Shigeyuki Oba(Kyoto Univ.)

Paper Information
Registration To Technical Committee on Neurocomputing / Technical Committee on Infomation-Based Induction Sciences and Machine Learning / IPSJ Special Interest Group on Mathematical Modeling and Problem Solving / IPSJ Special Interest Group on Bioinformatics and Genomics
Language JPN
Title (in Japanese) (See Japanese page)
Sub Title (in Japanese) (See Japanese page)
Title (in English) A sleep state analysis from calcium imaging data using non-negative matrix factorization
Sub Title (in English)
Keyword(1) Sleep
Keyword(2) Calcium Imaging
Keyword(3) Non-negative Matrix Factorization
1st Author's Name Mizuo Nagayama
1st Author's Affiliation Waseda University(Waseda Univ.)
2nd Author's Name Toshimitsu Aritake
2nd Author's Affiliation Waseda University(Waseda Univ.)
3rd Author's Name Hideitsu Hino
3rd Author's Affiliation The Institute of Statistical Mathematics(ISM)
4th Author's Name Takeshi Kanda
4th Author's Affiliation University of Tsukuba(Univ. of Tsukuba)
5th Author's Name Takehiro Miyazaki
5th Author's Affiliation University of Tsukuba(Univ. of Tsukuba)
6th Author's Name Masashi Yanagisawa
6th Author's Affiliation University of Tsukuba(Univ. of Tsukuba)
7th Author's Name Shotaro Akaho
7th Author's Affiliation National Institute of Advanced Industrial Science and Technology(AIST)
8th Author's Name Noboru Murata
8th Author's Affiliation Waseda University(Waseda Univ.)
Date 2019-06-18
Paper # NC2019-14,IBISML2019-12
Volume (vol) vol.119
Number (no) NC-88,IBISML-89
Page pp.pp.57-61(NC), pp.79-83(IBISML),
#Pages 5
Date of Issue 2019-06-10 (NC, IBISML)