| Presentation | 2019-01-23 Comparison of measured translational velocity of contrast agent with theoretical calculation in contrast enhanced ultrasound Kenji Yoshida, Katsuya Saito, Masaaki Omura, Tadashi Yamaguchi, |
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| PDF Download Page |  PDF download Page Link |
| Abstract(in Japanese) | (See Japanese page) |
| Abstract(in English) | This report proposes a method for detecting lymph channels, named contrast enhanced active Doppler ultrasonography(CEADUS), where ultrasound contrast agents (UCAs) are driven by acoustic radiation force and their translation are quantified by ultrasound pulse Doppler. In order to confirm the principle of CEADUS, phantom experiment and theoretical calculation were conducted. The cylindrical chamber with diameter of 0.5 mm was formed in agar gel phantom and Sonazoid? as UCAs was injected into the chamber. In the static condition, ultrasound pulse with center frequency of 14.4 MHz was repeatedly radiated during 10 seconds. The measurement was conducted in several conditions for peak negative pressure (Pnp) of ultrasound of 1.5, 2.2, 2.25 and 2.76 MPa and for pulse repetition frequency (PRF) of 0.1, 0.2, 1, 2 kHz. The Doppler signal was defined as the change of echo signal in the axis of pulse repetition time. The Doppler shift frequency was quantified by the frequency analysis of the Doppler signal and was converted into the translational velocity of UCAs assuming that UCAs traveled in the direction of propagation axis of ultrasound. As a result, it was shown that the peak value of translational velocity of UCAs in the chamber increased nonlinearly with increasing in Pnp and linearly with PRF. The peak value of translational velocity reached to 0.8 mm/s at Pnp=2.25 MPa and PRF=2 kHz. Numerical calculation for dynamical equations for oscillation and translation of a UCA was conducted in the same condition with experiments. The calculated translation velocity was proportional to the square of sound pressure amplitude and proportional to PRF. The calculation qualitatively and quantitatively agreed with the experimental result. These results prove that the proposed method is feasible in principle. |
| Keyword(in Japanese) | (See Japanese page) |
| Keyword(in English) | Doppler ultrasound / Ultrasound contrast agent / Acoustic radiation force / Pulse repetition frequency |
| Paper # | US2018-107 |
| Date of Issue | 2019-01-15 (US) |
| Conference Information | |
| Committee | EA / US |
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| Conference Date | 2019/1/22(2days) |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Doshisha Univ. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | [Joint Meeting on Acoustics and Ultrasonics Subsociety] Engineering/Electro Acoustics, Ultrasonics, and Related Topics |
| Chair | Suehiro Shimauchi(Kanazawa Inst. of Tech.) / Shinichi Takeuchi(Toin Univ. of Yokohama) |
| Vice Chair | Kenichi Furuya(Oita Univ.) / Kanji Watanabe(Akita Pref. Univ.) / Minoru Kurosawa(Tokyo Inst. of Tech.) / Jun Kondo(Shizuoka Univ.) |
| Secretary | Kenichi Furuya(Shizuoka Inst. of Science and Tech.) / Kanji Watanabe(NHK) / Minoru Kurosawa(Univ. of Tokyo) / Jun Kondo(Kanagawa Univ.) |
| Assistant | Keisuke Imoto(Ritsumeikan Univ.) / Daisuke Morikawa(Toyama Pref Univ.) / Daisuke Koyama(Doshisha Univ.) |
| Paper Information | |
| Registration To | Technical Committee on Engineering Acoustics / Technical Committee on Ultrasonics |
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| Language | JPN |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Comparison of measured translational velocity of contrast agent with theoretical calculation in contrast enhanced ultrasound |
| Sub Title (in English) | |
| Keyword(1) | Doppler ultrasound |
| Keyword(2) | Ultrasound contrast agent |
| Keyword(3) | Acoustic radiation force |
| Keyword(4) | Pulse repetition frequency |
| 1st Author's Name | Kenji Yoshida |
| 1st Author's Affiliation | Chiba University(Chiba Univ.) |
| 2nd Author's Name | Katsuya Saito |
| 2nd Author's Affiliation | Chiba University(Chiba Univ.) |
| 3rd Author's Name | Masaaki Omura |
| 3rd Author's Affiliation | Chiba University(Chiba Univ.) |
| 4th Author's Name | Tadashi Yamaguchi |
| 4th Author's Affiliation | Chiba University(Chiba Univ.) |
| Date | 2019-01-23 |
| Paper # | US2018-107 |
| Volume (vol) | vol.118 |
| Number (no) | US-409 |
| Page | pp.pp.141-146(US), |
| #Pages | 6 |
| Date of Issue | 2019-01-15 (US) |