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Paper Abstract and Keywords
Presentation 2020-12-14 16:20
The physiological protocol of temporary BBB opening by High Intensity Ultrasound -- To deliver the anti-cancer drug to the affected area of glioblastoma smoothly --
Kazuhide Okada (NTMC) US2020-55
Abstract (in Japanese) (See Japanese page) 
(in English) In case of one of serious brain tumour, glioblastoma whose cure rate is pretty low,
the promising therapy is to pass the anti-tumour drug from blood side to the brain side,
by irradiating ultrasound to BBB attached with the blood vessel in which microbubbles are filled by the intravenous injection prior to its therapy, to open TJ (tight junction) of BBB.
But BBB is the important path which transmit the lactate and the amino acid to the whole body. So it must be closed as soon as the said drug cross BBB. So, In this study how to open/ close BBB physically and concretely is discussed.
Keyword (in Japanese) (See Japanese page) 
(in English) glicoma / glioblastoma / HIFU / BBB / Tight Junction / microbubble / intravenous injection /  
Reference Info. IEICE Tech. Rep., vol. 120, no. 295, US2020-55, pp. 28-33, Dec. 2020.
Paper # US2020-55 
Date of Issue 2020-12-07 (US) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380
Copyright
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reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee US  
Conference Date 2020-12-14 - 2020-12-14 
Place (in Japanese) (See Japanese page) 
Place (in English) Online 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To US 
Conference Code 2020-12-US 
Language English (Japanese title is available) 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) The physiological protocol of temporary BBB opening by High Intensity Ultrasound 
Sub Title (in English) To deliver the anti-cancer drug to the affected area of glioblastoma smoothly 
Keyword(1) glicoma  
Keyword(2) glioblastoma  
Keyword(3) HIFU  
Keyword(4) BBB  
Keyword(5) Tight Junction  
Keyword(6) microbubble  
Keyword(7) intravenous injection  
Keyword(8)  
1st Author's Name Kazuhide Okada  
1st Author's Affiliation New Tokyo Medical College (NTMC)
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Speaker
Date Time 2020-12-14 16:20:00 
Presentation Time 25 
Registration for US 
Paper # IEICE-US2020-55 
Volume (vol) IEICE-120 
Number (no) no.295 
Page pp.28-33 
#Pages IEICE-6 
Date of Issue IEICE-US-2020-12-07 


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