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Paper Abstract and Keywords
Presentation 2019-03-06 15:30
Estimation of inhomogeneous shear modulus distribution based on measurements of the displacement field using MRI
Osamu Kojima, Takaaki Nara (The Univ. of Tokyo) MBE2018-115
Abstract (in Japanese) (See Japanese page) 
(in English) The stiffness (shear modulus) of an abnormal tissue (e.g. fibrotic tissue and cancerous tissue) is different from that of a normal tissue. Hence, it is important to estimate the shear modulus distribution for determining the position, shape, and degree of progress of such an abnormal tissue. One way to estimate the shear modulus distribution is by employing magnetic resonance elastography (MRE). In conventional MRE approaches, the displacement field induced by elastic waves is measured by employing magnetic resonance imaging (MRI) , and the shear modulus distribution is calculated on the basis of Navier's equation. However, owing to the assumption that the shear modulus is locally homogeneous, significant error in estimation can occur around the most important regions where elastic properties change discontinuously. Additionally, finite difference approximation of second order derivative terms of the displacement can cause vulnerability to noise. In this study, a novel method is proposed for estimating the shear modulus distribution from the ratio of the complex stress sum calculated through integration of the displacement data to the complex strain sum calculated from first order differentiation of the displacement data, where the real and imaginary components of the complex stress sum are deviatoric and shear stress, respectively, and those of the complex strain sum are deviatoric and shear strain, respectively. Furthermore, the robustness of the proposed method is also demonstrated in this study.
Keyword (in Japanese) (See Japanese page) 
(in English) MRI / MR elastography / shear modulus / inhomogeneous / Dbar equation / / /  
Reference Info. IEICE Tech. Rep., vol. 118, no. 469, MBE2018-115, pp. 147-152, March 2019.
Paper # MBE2018-115 
Date of Issue 2019-02-25 (MBE) 
ISSN Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee NC MBE  
Conference Date 2019-03-04 - 2019-03-06 
Place (in Japanese) (See Japanese page) 
Place (in English) University of Electro Communications 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To MBE 
Conference Code 2019-03-NC-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Estimation of inhomogeneous shear modulus distribution based on measurements of the displacement field using MRI 
Sub Title (in English)  
Keyword(1) MRI  
Keyword(2) MR elastography  
Keyword(3) shear modulus  
Keyword(4) inhomogeneous  
Keyword(5) Dbar equation  
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1st Author's Name Osamu Kojima  
1st Author's Affiliation The University of Tokyo (The Univ. of Tokyo)
2nd Author's Name Takaaki Nara  
2nd Author's Affiliation The University of Tokyo (The Univ. of Tokyo)
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Speaker Author-1 
Date Time 2019-03-06 15:30:00 
Presentation Time 25 minutes 
Registration for MBE 
Paper # MBE2018-115 
Volume (vol) vol.118 
Number (no) no.469 
Page pp.147-152 
#Pages
Date of Issue 2019-02-25 (MBE) 


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