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| Presentation | 2018-10-20 14:15 Behavioral testing and resting-state brain functional connectivity analysis of the methimazole-induced transient hypothyroidism mice Yuto Yoshida, Ryusei Uchida, Katsuya Uchida, Keiichi Itoi, Mitsuyuki Nakao, Norihiro Katayama (Tohoku Univ.)  MBE2018-33 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | Decreased thyroid function in the fetal and juvenile period causes mental retardation and motor function decline. In this study, open-field behavioral testing and resting-state functional connectivity (rsFC) analysis of the brain were performed on transient hypothyroidism mice prepared by pharmacological manipulation. The rsFC analysis revealed that the negative correlation between the secondary motor cortex and the parietal temporal association area was stronger in the low activity mice of the test group than the control group. These results suggest that a histological abnormality of the brain is expressed as a difference in the structure of the rsFC network of the brain. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | resting-state functional connectivity / growth-retarded hypothyroid mouse / IOS imaging / open field test / / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 118, no. 257, MBE2018-33, pp. 31-36, Oct. 2018. | |
| Paper # | MBE2018-33 | |
| Date of Issue | 2018-10-13 (MBE) | |
| ISSN | Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MBE2018-33 |
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| Conference Information | |
| Committee | NC MBE |
| Conference Date | 2018-10-19 - 2018-10-20 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Tohoku Univ. |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | |
| Paper Information | |
| Registration To | MBE |
| Conference Code | 2018-10-NC-MBE |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Behavioral testing and resting-state brain functional connectivity analysis of the methimazole-induced transient hypothyroidism mice |
| Sub Title (in English) | |
| Keyword(1) | resting-state functional connectivity |
| Keyword(2) | growth-retarded hypothyroid mouse |
| Keyword(3) | IOS imaging |
| Keyword(4) | open field test |
| Keyword(5) | |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Yuto Yoshida |
| 1st Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 2nd Author's Name | Ryusei Uchida |
| 2nd Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 3rd Author's Name | Katsuya Uchida |
| 3rd Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 4th Author's Name | Keiichi Itoi |
| 4th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 5th Author's Name | Mitsuyuki Nakao |
| 5th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 6th Author's Name | Norihiro Katayama |
| 6th Author's Affiliation | Tohoku University (Tohoku Univ.) |
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| Speaker | Author-1 |
| Date Time | 2018-10-20 14:15:00 |
| Presentation Time | 25 minutes |
| Registration for | MBE |
| Paper # | MBE2018-33 |
| Volume (vol) | vol.118 |
| Number (no) | no.257 |
| Page | pp.31-36 |
| #Pages | 6 |
| Date of Issue | 2018-10-13 (MBE) |
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