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Paper Abstract and Keywords
Presentation 2018-07-24 11:25
Photodynamic Diagnosis for Malignant Pleural Diseases using 5-Aminolevulinic acid and Auto fluorescence Imaging System
Masahiro Kitada, Yoshinobu Ohsaki, Shunsuke Yasuda, Nana Takahashi, Satoshi Okazaki, Kei Ishibashi (AMU) MI2018-25
Abstract (in Japanese) (See Japanese page) 
(in English) We have developed a new diagnostic method using the photosensitizer 5-aminolevulinic acid (5ALA) for diagnosing intrathoracic malignant lesions. When ingested exogenously, 5ALA is metabolized to a heme precursor, protoporphyrin IX, which stays in malignant cells and emits red to pink luminescence of about 630 nm. Malignant lesions on the pleural surface emitted pink autofluorescence in contrast to the green autofluorescence of the surrounding normal tissues observed by an autofluorescence imaging system. This system achieved accurate localization of malignant lesions, suggesting that it may also be applicable to photodynamic therapy.
Keyword (in Japanese) (See Japanese page) 
(in English) Malignant pleural disease, / Auto fluorescence / Photodynamic diagnosis / 5-Aminolevulnic acid(5ALA) / / / /  
Reference Info. IEICE Tech. Rep., vol. 118, no. 150, MI2018-25, pp. 17-20, July 2018.
Paper # MI2018-25 
Date of Issue 2018-07-17 (MI) 
ISSN Online edition: ISSN 2432-6380
Copyright
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reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF MI2018-25

Conference Information
Committee MI  
Conference Date 2018-07-24 - 2018-07-24 
Place (in Japanese) (See Japanese page) 
Place (in English) aiina (Morioka, Iwate) 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Medical Imaging, etc. 
Paper Information
Registration To MI 
Conference Code 2018-07-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Photodynamic Diagnosis for Malignant Pleural Diseases using 5-Aminolevulinic acid and Auto fluorescence Imaging System 
Sub Title (in English)  
Keyword(1) Malignant pleural disease,  
Keyword(2) Auto fluorescence  
Keyword(3) Photodynamic diagnosis  
Keyword(4) 5-Aminolevulnic acid(5ALA)  
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1st Author's Name Masahiro Kitada  
1st Author's Affiliation Asahikawa Medical University (AMU)
2nd Author's Name Yoshinobu Ohsaki  
2nd Author's Affiliation Asahikawa Medical University (AMU)
3rd Author's Name Shunsuke Yasuda  
3rd Author's Affiliation Asahikawa Medical University (AMU)
4th Author's Name Nana Takahashi  
4th Author's Affiliation Asahikawa Medical University (AMU)
5th Author's Name Satoshi Okazaki  
5th Author's Affiliation Asahikawa Medical University (AMU)
6th Author's Name Kei Ishibashi  
6th Author's Affiliation Asahikawa Medical University (AMU)
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Speaker Author-1 
Date Time 2018-07-24 11:25:00 
Presentation Time 20 minutes 
Registration for MI 
Paper # MI2018-25 
Volume (vol) vol.118 
Number (no) no.150 
Page pp.17-20 
#Pages
Date of Issue 2018-07-17 (MI) 


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