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Paper Abstract and Keywords
Presentation 2018-01-27 13:10

Kaima Okubo, Yusuke Tsuruno, Takahiro Fujiwara, Umihiro Inoue, Yoshihisa Yamaoka, Eiji Takahashi (Saga Univ.)
Abstract (in Japanese) (See Japanese page) 
(in English) To investigate the possibility that tumor cells migrate toward intratumor blood vessels according to the gradient of oxygen concentration in tissue, we devised the gap cover glass (GCG) that allows to produce gradients of oxygen in the monolayer cultured cells. To verify the oxygen gradients, we conducted oxygen imaging in the extracellular medium in cultured MDA-MB-231 and COS-7 cells using a ruthenium complex under conditions of different cell density, cell species, or cellular respiration, all of which significantly alter the oxygen consumption rate per unit volume of the cell. The measured oxygen gradients were consistent with the changes in the oxygen consumption rate. Thus, we conclude that the GCG produces gradients of oxygen in monolayer cultured cells.
Keyword (in Japanese) (See Japanese page) 
(in English) tumor cells / oxygen gradients / migration / oxygen imaging / / / /  
Reference Info. IEICE Tech. Rep., vol. 117, no. 416, MBE2017-75, pp. 47-52, Jan. 2018.
Paper # MBE2017-75 
Date of Issue 2018-01-19 (MBE) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380

Conference Information
Committee MBE NC NLP  
Conference Date 2018-01-26 - 2018-01-27 
Place (in Japanese) (See Japanese page) 
Place (in English) Kyushu Institute of Technology 
Topics (in Japanese) (See Japanese page) 
Topics (in English) ME, generalImplementation of Neuro Computing,Analysis and Modeling of Human Science, 
Paper Information
Registration To MBE 
Conference Code 2018-01-MBE-NC-NLP 
Language Japanese without English title) 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English)  
Sub Title (in English)  
Keyword(1) tumor cells  
Keyword(2) oxygen gradients  
Keyword(3) migration  
Keyword(4) oxygen imaging  
1st Author's Name Kaima Okubo  
1st Author's Affiliation Saga University (Saga Univ.)
2nd Author's Name Yusuke Tsuruno  
2nd Author's Affiliation Saga University (Saga Univ.)
3rd Author's Name Takahiro Fujiwara  
3rd Author's Affiliation Saga University (Saga Univ.)
4th Author's Name Umihiro Inoue  
4th Author's Affiliation Saga University (Saga Univ.)
5th Author's Name Yoshihisa Yamaoka  
5th Author's Affiliation Saga University (Saga Univ.)
6th Author's Name Eiji Takahashi  
6th Author's Affiliation Saga University (Saga Univ.)
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Date Time 2018-01-27 13:10:00 
Presentation Time 25 
Registration for MBE 
Paper # IEICE-MBE2017-75 
Volume (vol) IEICE-117 
Number (no) no.416 
Page pp.47-52 
#Pages IEICE-6 
Date of Issue IEICE-MBE-2018-01-19 

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