Paper Abstract and Keywords |
Presentation |
2017-11-24 14:55
Extracellular diffusion analysis in the mouse cortex using in vivo integrative optical imaging method Yui Hiroya, Kenya Tanaka, Yuto Yoshida (Tohoku Univ.), Akihiro Karashima (TOHTECH), Mitsuyuki Nakao, Norihiro Katayama (Tohoku Univ.) MBE2017-47 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
The brain has an unique waste clearance system, called glymphatic system, which is activated during sleep state. In order to know the mechanism of the state-dependency of the system, various methods were applied to measure diffusion property of brain parenchyma. However, the mechanism is still unknown due to the low time resolution of those methods. In this study, by using repetitive integrative optical imaging method, we measured the diffusion property of brain parenchyma in the primary somatosensory cortex of a mouse under the isoflurane anesthetized condition. As a result, we found that there is a drift of diffusion in brain parenchyma. In addition, we found weak correlation between variance of EEG and diffusion coefficient. These results suggest that directed cerebrospinal fluid flows in the brain and the diffusion property changes depending on the concentration of anesthesia. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
Glymphatic system / Extracellular space / Integrative Optical Imaging / / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 117, no. 324, MBE2017-47, pp. 5-8, Nov. 2017. |
Paper # |
MBE2017-47 |
Date of Issue |
2017-11-17 (MBE) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
Download PDF |
MBE2017-47 |
Conference Information |
Committee |
MBE NC |
Conference Date |
2017-11-24 - 2017-11-25 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
Tohoku University |
Topics (in Japanese) |
(See Japanese page) |
Topics (in English) |
BCI/BMI, generall |
Paper Information |
Registration To |
MBE |
Conference Code |
2017-11-MBE-NC |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
Extracellular diffusion analysis in the mouse cortex using in vivo integrative optical imaging method |
Sub Title (in English) |
|
Keyword(1) |
Glymphatic system |
Keyword(2) |
Extracellular space |
Keyword(3) |
Integrative Optical Imaging |
Keyword(4) |
|
Keyword(5) |
|
Keyword(6) |
|
Keyword(7) |
|
Keyword(8) |
|
1st Author's Name |
Yui Hiroya |
1st Author's Affiliation |
Tohoku University (Tohoku Univ.) |
2nd Author's Name |
Kenya Tanaka |
2nd Author's Affiliation |
Tohoku University (Tohoku Univ.) |
3rd Author's Name |
Yuto Yoshida |
3rd Author's Affiliation |
Tohoku University (Tohoku Univ.) |
4th Author's Name |
Akihiro Karashima |
4th Author's Affiliation |
Tohoku Institute of Technology (TOHTECH) |
5th Author's Name |
Mitsuyuki Nakao |
5th Author's Affiliation |
Tohoku University (Tohoku Univ.) |
6th Author's Name |
Norihiro Katayama |
6th Author's Affiliation |
Tohoku University (Tohoku Univ.) |
7th Author's Name |
|
7th Author's Affiliation |
() |
8th Author's Name |
|
8th Author's Affiliation |
() |
9th Author's Name |
|
9th Author's Affiliation |
() |
10th Author's Name |
|
10th Author's Affiliation |
() |
11th Author's Name |
|
11th Author's Affiliation |
() |
12th Author's Name |
|
12th Author's Affiliation |
() |
13th Author's Name |
|
13th Author's Affiliation |
() |
14th Author's Name |
|
14th Author's Affiliation |
() |
15th Author's Name |
|
15th Author's Affiliation |
() |
16th Author's Name |
|
16th Author's Affiliation |
() |
17th Author's Name |
|
17th Author's Affiliation |
() |
18th Author's Name |
|
18th Author's Affiliation |
() |
19th Author's Name |
|
19th Author's Affiliation |
() |
20th Author's Name |
|
20th Author's Affiliation |
() |
Speaker |
Author-1 |
Date Time |
2017-11-24 14:55:00 |
Presentation Time |
25 minutes |
Registration for |
MBE |
Paper # |
MBE2017-47 |
Volume (vol) |
vol.117 |
Number (no) |
no.324 |
Page |
pp.5-8 |
#Pages |
4 |
Date of Issue |
2017-11-17 (MBE) |
|