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Paper Abstract and Keywords
Presentation 2016-11-14 13:15
[Invited Talk] Molecular mechanism of cancer development by chromosome engineering technology -- Future efforts and possibilities of Chromosome Engineering Research Center (CERC) --
Hiroyuki Kugoh (Tottori Univ.) MI2016-67
Abstract (in Japanese) (See Japanese page) 
(in English) Chromosome engineering technique that base on Microcell-mediated chromosome transfer (MMCT), which can be generally used to the introduction of a single chromosome to a variety of tumor cells, is one of effective approach for mapping and identification of tumor suppressor genes. Using chromosome engineering technique that base on Microcell-mediated chromosome transfer (MMCT), we have identified paired-like homeodomain 1 (PITX1) gene as a novel telomerase negative regulatory factor that inhibit the expression of telomerase reverse transcriptase (TERT). Here, we describe a unique strategy to identification of tumor suppressor gene by using MMCT approach and introduce future efforts and possibilities of CERC.
Keyword (in Japanese) (See Japanese page) 
(in English) Chromosome Engineering / Artificial Chromosome / Microcell-mediated Chromosome Transfer (MMCT) / Tumor suppressor genes / / / /  
Reference Info. IEICE Tech. Rep., vol. 116, no. 298, MI2016-67, pp. 25-27, Nov. 2016.
Paper # MI2016-67 
Date of Issue 2016-11-07 (MI) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MI  
Conference Date 2016-11-14 - 2016-11-14 
Place (in Japanese) (See Japanese page) 
Place (in English) Tottori Univ. 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Medical Applications of Computer Vision Technology, Medical Imaging, etc. 
Paper Information
Registration To MI 
Conference Code 2016-11-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Molecular mechanism of cancer development by chromosome engineering technology 
Sub Title (in English) Future efforts and possibilities of Chromosome Engineering Research Center (CERC) 
Keyword(1) Chromosome Engineering  
Keyword(2) Artificial Chromosome  
Keyword(3) Microcell-mediated Chromosome Transfer (MMCT)  
Keyword(4) Tumor suppressor genes  
1st Author's Name Hiroyuki Kugoh  
1st Author's Affiliation Chromosome Engineering Research Center (CERC), Tottori University (Tottori Univ.)
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Date Time 2016-11-14 13:15:00 
Presentation Time 60 
Registration for MI 
Paper # IEICE-MI2016-67 
Volume (vol) IEICE-116 
Number (no) no.298 
Page pp.25-27 
#Pages IEICE-3 
Date of Issue IEICE-MI-2016-11-07 

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