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Paper Abstract and Keywords
Presentation 2016-07-05 16:00
A neuromarker of anxiety from whole-brain functional connectivity.
Yu Takagi (NAIST/ATR), Yuki Sakai (Kyoto Pref. Univ. Med./ATR), Saori C. Tanaka (ATR) NC2016-6
Abstract (in Japanese) (See Japanese page) 
(in English) There are times when an anxiety drives us to make an effort to achieve our goal and times when it may also harm our daily life. Previous studies have investigated neural substrates of anxiety by inspecting neural activities during a specific task or resting state. However, common neural substrates between task and resting state remain unclear. Here, to investigate “universal” neural substrates of anxiety by data driven procedures, we obtained human subjects’ neural activities by using functional magnetic resonance imaging (fMRI) during subjects saw both of anxious and neutral stimuli. We identified neural markers consisting of patterns of functional connectivity which serve to distinguish anxious states from neutral states. Further, we tried to predict individual’s daily anxiousness by applying the neural markers to the external resting-state fMRI. We show that our whole-brain anxiousness neural marker not only detect the anxious state during task, but also generalized to resting-state.
Keyword (in Japanese) (See Japanese page) 
(in English) fMRI / anxiety / resting-state brain activity / functional connectivity / machine learning / / /  
Reference Info. IEICE Tech. Rep., vol. 116, no. 120, NC2016-6, pp. 159-164, July 2016.
Paper # NC2016-6 
Date of Issue 2016-06-28 (NC) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
Copyright
and
reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF NC2016-6

Conference Information
Committee NC IPSJ-BIO IBISML IPSJ-MPS  
Conference Date 2016-07-04 - 2016-07-06 
Place (in Japanese) (See Japanese page) 
Place (in English) Okinawa Institute of Science and Technology 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Machine Learning Approach to Biodata Mining, and General 
Paper Information
Registration To NC 
Conference Code 2016-07-NC-BIO-IBISML-MPS 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) A neuromarker of anxiety from whole-brain functional connectivity. 
Sub Title (in English)  
Keyword(1) fMRI  
Keyword(2) anxiety  
Keyword(3) resting-state brain activity  
Keyword(4) functional connectivity  
Keyword(5) machine learning  
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1st Author's Name Yu Takagi  
1st Author's Affiliation Nara Institute of Science and Technology/Advanced Telecommunications Research Institute International (NAIST/ATR)
2nd Author's Name Yuki Sakai  
2nd Author's Affiliation Kyoto Prefectural University of Medicine/Advanced Telecommunications Research Institute International (Kyoto Pref. Univ. Med./ATR)
3rd Author's Name Saori C. Tanaka  
3rd Author's Affiliation Advanced Telecommunications Research Institute International (ATR)
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Speaker Author-1 
Date Time 2016-07-05 16:00:00 
Presentation Time 25 minutes 
Registration for NC 
Paper # NC2016-6 
Volume (vol) vol.116 
Number (no) no.120 
Page pp.159-164 
#Pages
Date of Issue 2016-06-28 (NC) 


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