Paper Abstract and Keywords |
Presentation |
2016-07-05 16:00
A neuromarker of anxiety from whole-brain functional connectivity. Yu Takagi (NAIST/ATR), Yuki Sakai (Kyoto Pref. Univ. Med./ATR), Saori C. Tanaka (ATR) NC2016-6 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
There are times when an anxiety drives us to make an effort to achieve our goal and times when it may also harm our daily life. Previous studies have investigated neural substrates of anxiety by inspecting neural activities during a specific task or resting state. However, common neural substrates between task and resting state remain unclear. Here, to investigate “universal” neural substrates of anxiety by data driven procedures, we obtained human subjects’ neural activities by using functional magnetic resonance imaging (fMRI) during subjects saw both of anxious and neutral stimuli. We identified neural markers consisting of patterns of functional connectivity which serve to distinguish anxious states from neutral states. Further, we tried to predict individual’s daily anxiousness by applying the neural markers to the external resting-state fMRI. We show that our whole-brain anxiousness neural marker not only detect the anxious state during task, but also generalized to resting-state. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
fMRI / anxiety / resting-state brain activity / functional connectivity / machine learning / / / |
Reference Info. |
IEICE Tech. Rep., vol. 116, no. 120, NC2016-6, pp. 159-164, July 2016. |
Paper # |
NC2016-6 |
Date of Issue |
2016-06-28 (NC) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
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NC2016-6 |
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