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Paper Abstract and Keywords
Presentation 2014-03-17 09:40
Regulation of acetylcholine to excitatory postsynaptic potential and spike back-propagation in hippocampal CA1 dendrite
Gaku Kaieda, Masashi Kondo, Takeshi Aihara (Tamagawa Univ)
Abstract (in Japanese) (See Japanese page) 
(in English) Acetylcholine (ACh) acts as a “modulator” on the initiation of synaptic plasticity. . The retrograde spikes called back-propagating action potentials (bAPs) is considered to play an important role in the initiation of synaptic plasticity. The purpose of this study was how acetylcholine influences the bAP along dendrites. To probe the spatio-temporal dynamics of bAP, we employed an optical imaging method with voltage-sensitive dye. As a result, the amplitude of bAP was suppressed by carbachol, acetylcholine receptor agonist.. Therefore, the synaptic plasticity along dendrites could be affected by means of the suppression of bAPs.
Keyword (in Japanese) (See Japanese page) 
(in English) back-propagating action potential / acetylcholine / EPSP(excitatory post-synaptic potential) / Optical imaging / voltage-sensitive dye / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 499, MBE2013-115, pp. 1-6, March 2014.
Paper # MBE2013-115 
Date of Issue 2014-03-10 (MBE) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380

Conference Information
Committee NC MBE  
Conference Date 2014-03-17 - 2014-03-18 
Place (in Japanese) (See Japanese page) 
Place (in English) Tamagawa University 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To MBE 
Conference Code 2014-03-NC-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Regulation of acetylcholine to excitatory postsynaptic potential and spike back-propagation in hippocampal CA1 dendrite 
Sub Title (in English)  
Keyword(1) back-propagating action potential  
Keyword(2) acetylcholine  
Keyword(3) EPSP(excitatory post-synaptic potential)  
Keyword(4) Optical imaging  
Keyword(5) voltage-sensitive dye  
1st Author's Name Gaku Kaieda  
1st Author's Affiliation Tamagawa University (Tamagawa Univ)
2nd Author's Name Masashi Kondo  
2nd Author's Affiliation Tamagawa University (Tamagawa Univ)
3rd Author's Name Takeshi Aihara  
3rd Author's Affiliation Tamagawa University (Tamagawa Univ)
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Date Time 2014-03-17 09:40:00 
Presentation Time 20 
Registration for MBE 
Paper # IEICE-MBE2013-115 
Volume (vol) IEICE-113 
Number (no) no.499 
Page pp.1-6 
#Pages IEICE-6 
Date of Issue IEICE-MBE-2014-03-10 

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