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Paper Abstract and Keywords
Presentation 2013-11-07 10:00
Development of automated estimation of four-dimensional dose distributions based on a 2D/3D registration during a high precision radiotherapy
Takahiro Nakamoto, Hidetaka Arimura, Katsumasa Nakamura (Kyushu Univ.), Yoshiyuki Shioyama (Saga HIMAT), Asumi Mizoguchi (Kurume Univ. Hospital), Taka-aki Hirose (Kyushu Univ. Hospital), Hiroshi Honda (Kyushu Univ.), Yoshiyuki Umedu, Yasuhiko Nakamura (Kyushu Univ. Hospital), Hideki Hirata (Kyushu Univ.) MI2013-46
Abstract (in Japanese) (See Japanese page) 
(in English) The purpose of this study was to develop an estimation method of four-dimensional (4D) dose distributions during radiotherapy based on a 2D/3D registration. “Treatment” computed tomography (CT) images were estimated by deforming three-dimensional (3D) planning CT images by using affine transformation matrices so that a two-dimensional (2D) planning portal dose image (PDI) can be similar to a certain time 2D dynamic clinical PDI. The planning PDI was calculated by applying a dose calculation method (convolution algorithm) to a geometry of the planning CT image and a virtual water phantom. The dynamic clinical PDI was estimated from electronic portal imaging device (EPID) dynamic image acquired during a treatment time. The parameters of affine transformation matrices were optimized by a Levenberg-Marquardt (LM) algorithm. Finally, the 4D dose distributions during the treatment time were calculated by applying the dose calculation method to the simulated 4D “treatment” CT images. The proposed method might be useful for assessment of the outcomes and risk management.
Keyword (in Japanese) (See Japanese page) 
(in English) High precision radiotherapy / CT images / 4D dose distributions / 2D/3D registration / / / /  
Reference Info. IEICE Tech. Rep., vol. 113, no. 281, MI2013-46, pp. 5-10, Nov. 2013.
Paper # MI2013-46 
Date of Issue 2013-10-31 (MI) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MI  
Conference Date 2013-11-07 - 2013-11-07 
Place (in Japanese) (See Japanese page) 
Place (in English)  
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To MI 
Conference Code 2013-11-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Development of automated estimation of four-dimensional dose distributions based on a 2D/3D registration during a high precision radiotherapy 
Sub Title (in English)  
Keyword(1) High precision radiotherapy  
Keyword(2) CT images  
Keyword(3) 4D dose distributions  
Keyword(4) 2D/3D registration  
1st Author's Name Takahiro Nakamoto  
1st Author's Affiliation Kyushu University (Kyushu Univ.)
2nd Author's Name Hidetaka Arimura  
2nd Author's Affiliation Kyushu University (Kyushu Univ.)
3rd Author's Name Katsumasa Nakamura  
3rd Author's Affiliation Kyushu University (Kyushu Univ.)
4th Author's Name Yoshiyuki Shioyama  
4th Author's Affiliation Saga Heavy Ion Medical Accelerator in Tosu (Saga HIMAT)
5th Author's Name Asumi Mizoguchi  
5th Author's Affiliation Kurume University Hospital (Kurume Univ. Hospital)
6th Author's Name Taka-aki Hirose  
6th Author's Affiliation Kyushu University Hospital (Kyushu Univ. Hospital)
7th Author's Name Hiroshi Honda  
7th Author's Affiliation Kyushu University (Kyushu Univ.)
8th Author's Name Yoshiyuki Umedu  
8th Author's Affiliation Kyushu University Hospital (Kyushu Univ. Hospital)
9th Author's Name Yasuhiko Nakamura  
9th Author's Affiliation Kyushu University Hospital (Kyushu Univ. Hospital)
10th Author's Name Hideki Hirata  
10th Author's Affiliation Kyushu University (Kyushu Univ.)
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Date Time 2013-11-07 10:00:00 
Presentation Time 30 
Registration for MI 
Paper # IEICE-MI2013-46 
Volume (vol) IEICE-113 
Number (no) no.281 
Page pp.5-10 
#Pages IEICE-6 
Date of Issue IEICE-MI-2013-10-31 

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