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| Presentation | 2013-01-25 13:10 Influence of MRI-based attenuation correction methods on quantitative analysis of brain PET Hiroshi Kawaguchi (NIRS), Asuka Tanigawa, Mikio Suga (Chiba Univ.), Yoshiyuki Hirano, Takahiro Shiraishi, Eiji Yoshida, Yasuyuki Kimura, Katsuyuki Tanimoto, Takayuki Obata, Hiroshi Ito, Taiga Yamaya (NIRS)  MI2012-108 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | The quantitative capability is fundamental for PET in the human brain. Several attenuation correction methods for PET/MRI scanner have been reported, however, the influence of the methods on quantitative values in reconstructed PET images has not been investigated well. In addition, the adequacy in attenuation coefficient being assigned is also ambiguous. In this study, we evaluated the effects of attenuation correction methods on the quantification of 18F-FDG-PET in the human brain. Furthermore, the dependency of quantitative value was also investigated by perturbing the assignment of attenuation coefficient. The results indicated that the quantitative values on reconstructed PET image depended on the attenuation correction methods. The error in attenuation coefficient of the brain caused larger error in the quantitative PET value than that of the bone and soft tissues did. Moreover, the influence of an incorrect attenuation coefficient for brain is larger in deep gray matter, such as the striatum and thalamus, than in the occipital and temporal cortices. In contrast, an incorrect attenuation coefficient for bone and superficial soft tissue has a larger influence on cortical pixel intensities than on those in deep gray matter. The 10% error in the attenuation coefficients being assigned to brain regions caused around 6 to 8% error on the radioactivity of PET images. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | PET/MRI / attenuation correction for PET / human brain PET / / / / / | |
| Reference Info. | IEICE Tech. Rep., vol. 112, no. 411, MI2012-108, pp. 239-244, Jan. 2013. | |
| Paper # | MI2012-108 | |
| Date of Issue | 2013-01-17 (MI) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | MI2012-108 |
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| Conference Information | |
| Committee | MI |
| Conference Date | 2013-01-24 - 2013-01-25 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | Bunka Tenbusu Kan |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Computational anatomy and its application to computer assisted diagnosis and therapy, etc |
| Paper Information | |
| Registration To | MI |
| Conference Code | 2013-01-MI |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Influence of MRI-based attenuation correction methods on quantitative analysis of brain PET |
| Sub Title (in English) | |
| Keyword(1) | PET/MRI |
| Keyword(2) | attenuation correction for PET |
| Keyword(3) | human brain PET |
| Keyword(4) | |
| Keyword(5) | |
| Keyword(6) | |
| Keyword(7) | |
| Keyword(8) | |
| 1st Author's Name | Hiroshi Kawaguchi |
| 1st Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 2nd Author's Name | Asuka Tanigawa |
| 2nd Author's Affiliation | Chiba University (Chiba Univ.) |
| 3rd Author's Name | Mikio Suga |
| 3rd Author's Affiliation | Chiba University (Chiba Univ.) |
| 4th Author's Name | Yoshiyuki Hirano |
| 4th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 5th Author's Name | Takahiro Shiraishi |
| 5th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 6th Author's Name | Eiji Yoshida |
| 6th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 7th Author's Name | Yasuyuki Kimura |
| 7th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 8th Author's Name | Katsuyuki Tanimoto |
| 8th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 9th Author's Name | Takayuki Obata |
| 9th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 10th Author's Name | Hiroshi Ito |
| 10th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
| 11th Author's Name | Taiga Yamaya |
| 11th Author's Affiliation | National Institute of Radiological Sciences (NIRS) |
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| Speaker | Author-1 |
| Date Time | 2013-01-25 13:10:00 |
| Presentation Time | 20 minutes |
| Registration for | MI |
| Paper # | MI2012-108 |
| Volume (vol) | vol.112 |
| Number (no) | no.411 |
| Page | pp.239-244 |
| #Pages | 6 |
| Date of Issue | 2013-01-17 (MI) |
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