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Paper Abstract and Keywords
Presentation 2013-01-24 16:00
Time delay correction method for PET-based tumor tracking
Tetsuya Shinaji (Chiba Univ.), Hideaki Tashima, Eiji Yoshida, Hideo Murayama, Taiga Yamaya (NIRS), Hideaki Haneishi (Chiba Univ.) MI2012-87
Abstract (in Japanese) (See Japanese page) 
(in English) The world’s first open type PET, named OpenPET, is being developed at the National Institute Radiological Sciences. We are aiming to employ the OpenPET in radiotherapy and to track the respiratory motion of a tumor in the thoracoabdominal region of a patient. By using PET images, we expect that the tumor itself can be directly visualized without using radio-opaque markers, but this goal has not been achieved yet. Our demonstration results using a small prototype OpenPET system showed that the system can output reconstructed images at about 2 frames per second with about a 2 s delay; this delay is mainly due to the reconstruction calculation time. In this study, we developed a time delay correction method for tumor tracking for the OpenPET. Since it is difficult to correct the time delay using only the tumor location 2 s before, we introduced another sensor to acquire the respiration phase for correction. In the proposed method, the relationship between tumor motion and the additional sensor output signal was calculated by support vector regression and the time delay was corrected by using the regression line which represents the relationship. In addition, to improve the accuracy of the prediction, we introduced the gates which evaluate accuracy of regression lines based on the contribution ratio and prediction interval. We simulated this time delay correction method with 4D XCAT phantom which had practical respiration motions obtained from clinical MRI. As a result, we could track the tumor within almost 1.5 mm mean error. We also found from the simulation that disturbance of the relationship can be detected by gates. Thus we could avoid the tracking errors which are caused by disturbance of the correlation.
Keyword (in Japanese) (See Japanese page) 
(in English) PET / OpenPET / Real-time imaging / Tumor tracking / Image guided radio therapy / / /  
Reference Info. IEICE Tech. Rep., vol. 112, no. 411, MI2012-87, pp. 129-133, Jan. 2013.
Paper # MI2012-87 
Date of Issue 2013-01-17 (MI) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (No. 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF MI2012-87

Conference Information
Committee MI  
Conference Date 2013-01-24 - 2013-01-25 
Place (in Japanese) (See Japanese page) 
Place (in English) Bunka Tenbusu Kan 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Computational anatomy and its application to computer assisted diagnosis and therapy, etc 
Paper Information
Registration To MI 
Conference Code 2013-01-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Time delay correction method for PET-based tumor tracking 
Sub Title (in English)  
Keyword(1) PET  
Keyword(2) OpenPET  
Keyword(3) Real-time imaging  
Keyword(4) Tumor tracking  
Keyword(5) Image guided radio therapy  
1st Author's Name Tetsuya Shinaji  
1st Author's Affiliation Chiba University (Chiba Univ.)
2nd Author's Name Hideaki Tashima  
2nd Author's Affiliation National Institute of Radiological Sciences (NIRS)
3rd Author's Name Eiji Yoshida  
3rd Author's Affiliation National Institute of Radiological Sciences (NIRS)
4th Author's Name Hideo Murayama  
4th Author's Affiliation National Institute of Radiological Sciences (NIRS)
5th Author's Name Taiga Yamaya  
5th Author's Affiliation National Institute of Radiological Sciences (NIRS)
6th Author's Name Hideaki Haneishi  
6th Author's Affiliation Chiba University (Chiba Univ.)
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Date Time 2013-01-24 16:00:00 
Presentation Time 15 
Registration for MI 
Paper # IEICE-MI2012-87 
Volume (vol) IEICE-112 
Number (no) no.411 
Page pp.129-133 
#Pages IEICE-5 
Date of Issue IEICE-MI-2013-01-17 

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