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Paper Abstract and Keywords
Presentation 2012-01-28 10:20
Frequency-Dependent Effects on ERP P300 by Repetitive Transcranial Magnetic Stimulation
Aya Sato, Tetsuya Torii, Masakuni Iwahashi (Junshin Gakuen Univ.), Keiji Iramina (Kyushu Univ.) MBE2011-94
Abstract (in Japanese) (See Japanese page) 
(in English) The present study analyzed the effects of repetitive transcranial magnetic stimulation (rTMS) on brain activity. P300 latency of event-related potential (ERP) was used to evaluate the effect of low-frequency and short-term rTMS by SMG (supramarginal gyrus) and DLPFC (dorsolateral prefrontal cortex), which is considered to be the related area of P300 origin. A figure-eight coil was used to stimulate left-right SMG and left-right DLPFC, and the intensity of magnetic stimulation was 80% of subject’s motor threshold. A total of 100-magnetic pulses were applied for rTMS. The effects of stimulus frequency at 1 or 0.5 Hz were determined. Following rTMS, the odd-ball task was performed and P300 latency of ERP was measured. ERP was measured prior to magnetic stimulation as a control. With 1 Hz low-frequency magnetic stimulation to the left SMG, P300 latency decreased. Compared to the control, the latency time difference was approximately 25 ms at Cz. In contrast, 0.5 Hz rTMS resulted in delayed P300 latency. Compared to the control, the latency time difference was approximately 17 ms at Cz. With 1-Hz low-frequency magnetic stimulation to the left DLPFC, P300 latency increased. Compared to the control, the latency time difference was approximately 26 ms at Cz. In contrast, 0.5 Hz rTMS resulted in maintained P300 latency. However, with sham at 1 or 0.5 Hz rTMS, the change of P300 latency wasn’t observed. As a result, P300 latency was varied according to rTMS frequency and rTMS stimulation point.
Keyword (in Japanese) (See Japanese page) 
(in English) repetitive transcranial magnetic stimulation / supramarginal gyrus / dorsolateral prefrontal cortex / event-related potential / P300 latency / frequency-dependent / /  
Reference Info. IEICE Tech. Rep., vol. 111, no. 423, MBE2011-94, pp. 83-87, Jan. 2012.
Paper # MBE2011-94 
Date of Issue 2012-01-20 (MBE) 
ISSN Print edition: ISSN 0913-5685    Online edition: ISSN 2432-6380
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All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
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Conference Information
Committee MBE  
Conference Date 2012-01-27 - 2012-01-28 
Place (in Japanese) (See Japanese page) 
Place (in English) Kyushu University 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To MBE 
Conference Code 2012-01-MBE 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Frequency-Dependent Effects on ERP P300 by Repetitive Transcranial Magnetic Stimulation 
Sub Title (in English)  
Keyword(1) repetitive transcranial magnetic stimulation  
Keyword(2) supramarginal gyrus  
Keyword(3) dorsolateral prefrontal cortex  
Keyword(4) event-related potential  
Keyword(5) P300 latency  
Keyword(6) frequency-dependent  
Keyword(7)  
Keyword(8)  
1st Author's Name Aya Sato  
1st Author's Affiliation Junshin Gakuen University (Junshin Gakuen Univ.)
2nd Author's Name Tetsuya Torii  
2nd Author's Affiliation Junshin Gakuen University (Junshin Gakuen Univ.)
3rd Author's Name Masakuni Iwahashi  
3rd Author's Affiliation Junshin Gakuen University (Junshin Gakuen Univ.)
4th Author's Name Keiji Iramina  
4th Author's Affiliation Kyushu University (Kyushu Univ.)
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Speaker Author-1 
Date Time 2012-01-28 10:20:00 
Presentation Time 25 minutes 
Registration for MBE 
Paper # MBE2011-94 
Volume (vol) vol.111 
Number (no) no.423 
Page pp.83-87 
#Pages
Date of Issue 2012-01-20 (MBE) 


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