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Paper Abstract and Keywords
Presentation 2010-01-28 11:40
Computer-aided Classification of Patients with Dementia of Alzheimer's Type Based on Cerebral Blood Flow Map Determined by Arterial Spin Labeling
Yasuo Yamashita, Hidetaka Arimura, Takashi Yoshiura, Taiki Magome, Koji Kobayashi, Akira Monji, Fukai Toyofuku, Masafumi Ohki, Yasuhiko Nakamura, Hiroshi Honda (Kyushu Univ.)
Abstract (in Japanese) (See Japanese page) 
(in English) Arterial spin labeling (ASL) is one of MR imaging techniques for measurement of cerebral blood flow (CBF) without using the contrast medium. The CBF map image measured by the ASL imaging can be used to help discriminate individuals with Alzheimer’s disease (AD) from normal subjects. We have developed a computerized classification method for patients with AD based on CBF map obtained by the ASL technique. The average CBFs in cortical regions of cerebral lobes were determined by using a free-form deformation between ALS image and the Talairach brain atlas. Finally, an artificial neural network, which was trained by the average CBFs in cortical regions, was employed for distinguishing patients with AD from control subjects. We applied the proposed method to 10 patients with AD and 10 control subjects. As a result, all cases could be classified correctly in the evaluation of resubstitution test.
Keyword (in Japanese) (See Japanese page) 
(in English) Alzheimer’s disease (AD) / arterial spin labeling (ASL) / computer-aided diagnosis / / / / /  
Reference Info. IEICE Tech. Rep., vol. 109, no. 407, MI2009-95, pp. 107-109, Jan. 2010.
Paper # MI2009-95 
Date of Issue 2010-01-21 (MI) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380

Conference Information
Committee MI  
Conference Date 2010-01-28 - 2010-01-29 
Place (in Japanese) (See Japanese page) 
Place (in English) Naha-Bunka-Tenbusu 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Medical Imaging 
Paper Information
Registration To MI 
Conference Code 2010-01-MI 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Computer-aided Classification of Patients with Dementia of Alzheimer's Type Based on Cerebral Blood Flow Map Determined by Arterial Spin Labeling 
Sub Title (in English)  
Keyword(1) Alzheimer’s disease (AD)  
Keyword(2) arterial spin labeling (ASL)  
Keyword(3) computer-aided diagnosis  
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1st Author's Name Yasuo Yamashita  
1st Author's Affiliation Kyushu University (Kyushu Univ.)
2nd Author's Name Hidetaka Arimura  
2nd Author's Affiliation Kyushu University (Kyushu Univ.)
3rd Author's Name Takashi Yoshiura  
3rd Author's Affiliation Kyushu University (Kyushu Univ.)
4th Author's Name Taiki Magome  
4th Author's Affiliation Kyushu University (Kyushu Univ.)
5th Author's Name Koji Kobayashi  
5th Author's Affiliation Kyushu University (Kyushu Univ.)
6th Author's Name Akira Monji  
6th Author's Affiliation Kyushu University (Kyushu Univ.)
7th Author's Name Fukai Toyofuku  
7th Author's Affiliation Kyushu University (Kyushu Univ.)
8th Author's Name Masafumi Ohki  
8th Author's Affiliation Kyushu University (Kyushu Univ.)
9th Author's Name Yasuhiko Nakamura  
9th Author's Affiliation Kyushu University (Kyushu Univ.)
10th Author's Name Hiroshi Honda  
10th Author's Affiliation Kyushu University (Kyushu Univ.)
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Speaker
Date Time 2010-01-28 11:40:00 
Presentation Time 30 
Registration for MI 
Paper # IEICE-MI2009-95 
Volume (vol) IEICE-109 
Number (no) no.407 
Page pp.107-109 
#Pages IEICE-3 
Date of Issue IEICE-MI-2010-01-21 


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