IEICE Technical Committee Submission System
Conference Paper's Information
Online Proceedings
[Sign in]
Tech. Rep. Archives
 Go Top Page Go Previous   [Japanese] / [English] 

Paper Abstract and Keywords
Presentation 2009-10-16 14:50
Algorithm for Finding Minimum Reaction Cut of Metabolic Network
Takeyuki Tamura (Kyoto Univ.), Kazuhiro Takemoto (Univ. of Tokyo.), Tatsuya Akutsu (Kyoto Univ.) COMP2009-36
Abstract (in Japanese) (See Japanese page) 
(in English) In this article, we study two problems ReactionCut and MD-ReactionCut
for calculating minimum reaction cuts of a metabolic network under a Boolean model.
These problems are based on flux balance model and minimal damage model respectively.
We show that ReactionCut and MD-ReactionCut are NP-hard even if the maximum outdegree of reaction nodes ($K_{out}$)
is one.
We also present $O(1.822^n)$, $O(1.959^n)$ and $o(2^n)$ time algorithms
for MD-ReactionCut with $K_{out}=2, 3, k$ respectively where
$n$ is the number of reaction nodes and $k$ is a constant.
The same algorithms also work for ReactionCut if there is no cycle.
Keyword (in Japanese) (See Japanese page) 
(in English) Metabolic network / Reaction cut / Boolean model / Robustness / / / /  
Reference Info. IEICE Tech. Rep., vol. 109, no. 235, COMP2009-36, pp. 27-34, Oct. 2009.
Paper # COMP2009-36 
Date of Issue 2009-10-09 (COMP) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380
Copyright
and
reproduction
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034)
Download PDF COMP2009-36

Conference Information
Committee COMP  
Conference Date 2009-10-16 - 2009-10-16 
Place (in Japanese) (See Japanese page) 
Place (in English) Tohoku University 
Topics (in Japanese) (See Japanese page) 
Topics (in English)  
Paper Information
Registration To COMP 
Conference Code 2009-10-COMP 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Algorithm for Finding Minimum Reaction Cut of Metabolic Network 
Sub Title (in English)  
Keyword(1) Metabolic network  
Keyword(2) Reaction cut  
Keyword(3) Boolean model  
Keyword(4) Robustness  
Keyword(5)  
Keyword(6)  
Keyword(7)  
Keyword(8)  
1st Author's Name Takeyuki Tamura  
1st Author's Affiliation Kyoto University (Kyoto Univ.)
2nd Author's Name Kazuhiro Takemoto  
2nd Author's Affiliation The University of Tokyo (Univ. of Tokyo.)
3rd Author's Name Tatsuya Akutsu  
3rd Author's Affiliation Kyoto University (Kyoto Univ.)
4th Author's Name  
4th Author's Affiliation ()
5th Author's Name  
5th Author's Affiliation ()
6th Author's Name  
6th Author's Affiliation ()
7th Author's Name  
7th Author's Affiliation ()
8th Author's Name  
8th Author's Affiliation ()
9th Author's Name  
9th Author's Affiliation ()
10th Author's Name  
10th Author's Affiliation ()
11th Author's Name  
11th Author's Affiliation ()
12th Author's Name  
12th Author's Affiliation ()
13th Author's Name  
13th Author's Affiliation ()
14th Author's Name  
14th Author's Affiliation ()
15th Author's Name  
15th Author's Affiliation ()
16th Author's Name  
16th Author's Affiliation ()
17th Author's Name  
17th Author's Affiliation ()
18th Author's Name  
18th Author's Affiliation ()
19th Author's Name  
19th Author's Affiliation ()
20th Author's Name  
20th Author's Affiliation ()
Speaker
Date Time 2009-10-16 14:50:00 
Presentation Time 35 
Registration for COMP 
Paper # IEICE-COMP2009-36 
Volume (vol) IEICE-109 
Number (no) no.235 
Page pp.27-34 
#Pages IEICE-8 
Date of Issue IEICE-COMP-2009-10-09 


[Return to Top Page]

[Return to IEICE Web Page]


The Institute of Electronics, Information and Communication Engineers (IEICE), Japan