Paper Abstract and Keywords |
Presentation |
2009-03-10 15:20
Variability of Rhythms in a Cardiac Pacemaker Cell Model Zhenxing Pan, Rei Yamaguchi, Masato Senoo, Shinji Doi (Osaka Univ.) NLP2008-160 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
A heart repeats contraction and relaxation, and these motions are controlled by electrical stimuli (action potential). The electrical stimuli are generated in sinoatrial node (cardiac pacemaker) and propagated to whole heart. Since the abnormality of rhythm (frequency of action potential generation) in sinoatrial node causes serious arrhythmia such as tachycardia, it is necessary to analyze the variability of rhythms. The Yanagihara-Noma-Irisawa (YNI) model of sinoatrial-node cells is described by the Hodgkin-Huxley-type equations with seven variables. In this model, the characteristics of membrane potential and rhythm significantly depends on the variation of parameter. In this research, we focus mainly on the variability of rhythm and analyze the global bifurcation structure of the YNI model by varying the conductances of ionic channels. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
cardiac pacemaker cell / sinoatrial node / ionic channel / Yanagihara-Noma-Irisawa model / bifurcation structure / drug sensitivity / / |
Reference Info. |
IEICE Tech. Rep., vol. 108, no. 477, NLP2008-160, pp. 53-58, March 2009. |
Paper # |
NLP2008-160 |
Date of Issue |
2009-03-03 (NLP) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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NLP2008-160 |
Conference Information |
Committee |
NLP |
Conference Date |
2009-03-10 - 2009-03-11 |
Place (in Japanese) |
(See Japanese page) |
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(See Japanese page) |
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Paper Information |
Registration To |
NLP |
Conference Code |
2009-03-NLP |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
Variability of Rhythms in a Cardiac Pacemaker Cell Model |
Sub Title (in English) |
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Keyword(1) |
cardiac pacemaker cell |
Keyword(2) |
sinoatrial node |
Keyword(3) |
ionic channel |
Keyword(4) |
Yanagihara-Noma-Irisawa model |
Keyword(5) |
bifurcation structure |
Keyword(6) |
drug sensitivity |
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1st Author's Name |
Zhenxing Pan |
1st Author's Affiliation |
Osaka University (Osaka Univ.) |
2nd Author's Name |
Rei Yamaguchi |
2nd Author's Affiliation |
Osaka University (Osaka Univ.) |
3rd Author's Name |
Masato Senoo |
3rd Author's Affiliation |
Osaka University (Osaka Univ.) |
4th Author's Name |
Shinji Doi |
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Osaka University (Osaka Univ.) |
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Speaker |
Author-1 |
Date Time |
2009-03-10 15:20:00 |
Presentation Time |
25 minutes |
Registration for |
NLP |
Paper # |
NLP2008-160 |
Volume (vol) |
vol.108 |
Number (no) |
no.477 |
Page |
pp.53-58 |
#Pages |
6 |
Date of Issue |
2009-03-03 (NLP) |
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