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| Presentation | 2007-08-10 11:30 Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress Michio Murakoshi, Naohiro Yoshida, Yoko Kitsunai, Koji Iida, Shun Kumano, Takashi Suzuki, Toshimitsu Kobayashi, Hiroshi Wada (Tohoku Univ.)  EA2007-49 |
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| Abstract | (in Japanese) | (See Japanese page) |
| (in English) | Noise-induced hearing loss was reported to be decreased by raising the body temperature before traumatic noise exposure, i.e., heat stress. However, the protective mechanism of the inner ear against such traumatic exposure remains unknown. In the present study, the mechanical properties and the amount of filamentous actin of outer hair cells (OHCs) in mice with or without heat stress were measured by atomic force microscopy and confocal laser scanning microscopy, respectively. The conditioning by heat stress caused an increase in F-actin of the OHCs, leading to an increase in their Young’s modulus. These results suggest that OHCs exposed to prior heat stress possibly experience less strain when they are exposed to loud noise, resulting in protection from traumatic noise exposure. | |
| Keyword | (in Japanese) | (See Japanese page) |
| (in English) | Heat Stress / Outer Hair Cell / Young's Modulus / Filamentous Actin / Prestin / Heat Shock Protein / Distortion Product Otoacoustic Emission / Atomic Force Microscopy | |
| Reference Info. | IEICE Tech. Rep., vol. 107, no. 187, EA2007-49, pp. 19-24, Aug. 2007. | |
| Paper # | EA2007-49 | |
| Date of Issue | 2007-08-03 (EA) | |
| ISSN | Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 | |
| Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) | |
| Download PDF | EA2007-49 |
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| Conference Information | |
| Committee | EA |
| Conference Date | 2007-08-09 - 2007-08-10 |
| Place (in Japanese) | (See Japanese page) |
| Place (in English) | School of Engineering, Tohoku University |
| Topics (in Japanese) | (See Japanese page) |
| Topics (in English) | Hearing, Audio Signal Processing, etc. |
| Paper Information | |
| Registration To | EA |
| Conference Code | 2007-08-EA |
| Language | Japanese |
| Title (in Japanese) | (See Japanese page) |
| Sub Title (in Japanese) | (See Japanese page) |
| Title (in English) | Protective mechanism of the inner ear from traumatic noise exposure actuated by heat stress |
| Sub Title (in English) | |
| Keyword(1) | Heat Stress |
| Keyword(2) | Outer Hair Cell |
| Keyword(3) | Young's Modulus |
| Keyword(4) | Filamentous Actin |
| Keyword(5) | Prestin |
| Keyword(6) | Heat Shock Protein |
| Keyword(7) | Distortion Product Otoacoustic Emission |
| Keyword(8) | Atomic Force Microscopy |
| 1st Author's Name | Michio Murakoshi |
| 1st Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 2nd Author's Name | Naohiro Yoshida |
| 2nd Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 3rd Author's Name | Yoko Kitsunai |
| 3rd Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 4th Author's Name | Koji Iida |
| 4th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 5th Author's Name | Shun Kumano |
| 5th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 6th Author's Name | Takashi Suzuki |
| 6th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 7th Author's Name | Toshimitsu Kobayashi |
| 7th Author's Affiliation | Tohoku University (Tohoku Univ.) |
| 8th Author's Name | Hiroshi Wada |
| 8th Author's Affiliation | Tohoku University (Tohoku Univ.) |
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| Speaker | Author-1 |
| Date Time | 2007-08-10 11:30:00 |
| Presentation Time | 30 minutes |
| Registration for | EA |
| Paper # | EA2007-49 |
| Volume (vol) | vol.107 |
| Number (no) | no.187 |
| Page | pp.19-24 |
| #Pages | 6 |
| Date of Issue | 2007-08-03 (EA) |
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