Paper Abstract and Keywords |
Presentation |
2007-06-08 14:50
On the global bifurcation structure of a detailed ventricular myocardial cell model and drug sensitivity of ionic channels Rei Yamaguchi, Shinji Doi, Sadatoshi Kumagai (Osaka Univ.) NLP2007-15 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
The Luo-Rudy dynamic model is a detailed ventricular myocardial
cell model which describes the temporal variation of cell membrane
potential.
This model is described by the Hodgkin-Huxley-type equations with 21
variables, and the membrane potential significantly depends on the variations of parameters.
In this research, we analyze the global bifurcation structure of the
Luo-Rudy dynamic model by varying the maximum conductances or parameters which play the same role as the maximum
conductances of ionic channels, and thus we investigate drug sensitivity of
ionic channels. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
ionic channel / channelopathy / Luo-Rudy dynamic model / bifurcation structure / drug sensitivity / / / |
Reference Info. |
IEICE Tech. Rep., vol. 107, no. 86, NLP2007-15, pp. 23-28, June 2007. |
Paper # |
NLP2007-15 |
Date of Issue |
2007-06-01 (NLP) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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NLP2007-15 |
Conference Information |
Committee |
NLP |
Conference Date |
2007-06-08 - 2007-06-09 |
Place (in Japanese) |
(See Japanese page) |
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Paper Information |
Registration To |
NLP |
Conference Code |
2007-06-NLP |
Language |
Japanese |
Title (in Japanese) |
(See Japanese page) |
Sub Title (in Japanese) |
(See Japanese page) |
Title (in English) |
On the global bifurcation structure of a detailed ventricular myocardial cell model and drug sensitivity of ionic channels |
Sub Title (in English) |
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Keyword(1) |
ionic channel |
Keyword(2) |
channelopathy |
Keyword(3) |
Luo-Rudy dynamic model |
Keyword(4) |
bifurcation structure |
Keyword(5) |
drug sensitivity |
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1st Author's Name |
Rei Yamaguchi |
1st Author's Affiliation |
Osaka University (Osaka Univ.) |
2nd Author's Name |
Shinji Doi |
2nd Author's Affiliation |
Osaka University (Osaka Univ.) |
3rd Author's Name |
Sadatoshi Kumagai |
3rd Author's Affiliation |
Osaka University (Osaka Univ.) |
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Speaker |
Author-1 |
Date Time |
2007-06-08 14:50:00 |
Presentation Time |
25 minutes |
Registration for |
NLP |
Paper # |
NLP2007-15 |
Volume (vol) |
vol.107 |
Number (no) |
no.86 |
Page |
pp.23-28 |
#Pages |
6 |
Date of Issue |
2007-06-01 (NLP) |
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