IEICE Technical Committee Submission System
Conference Paper's Information
Online Proceedings
[Sign in]
Tech. Rep. Archives
 Go Top Page Go Previous   [Japanese] / [English] 

Paper Abstract and Keywords
Presentation 2007-03-14 14:50
Inhibition-dominated network can explain multistability and highly irregular states in prefrontal cortex activity
Kosuke Hamaguchi (RIKEN), Nicolas Brunel (CNRS)
Abstract (in Japanese) (See Japanese page) 
(in English) During the delay response tasks of monkeys, some cells in the prefrontal cortex show cue position dependent persistent activity during the delay periods.
Recent analysis of these spike data has shown that the degree of spiking irregularity is also high during the persistent activity.
The high spike irregularity can be obtained by the external input with balanced excitation and inhibition. It is, however, not easy to obtain the self-sustained states with the balanced input because the mean level of recurrent input is not depolarizing.
Here it remains unclear how to achieve simultaneously bistability and high spike train irregularity.
Here we report the followings 1) Hopf-bifurcation lines exist before the bistable region which is calculated from the self-consistent analysis for Leaky Integrate-and-Fire (LIF) neuron with instantaneous synapses.
This indicates that the bistability is unstable in numerical simulations.
2) The self-consistent analysis for the LIF neuron network with exponential-decay synapses shows the bistable phase of localized bump states and quiescent states even in the inhibition-dominated region with sub-threshold external input.
Numerical simulations also show the bistability and high CV in these regions.
Keyword (in Japanese) (See Japanese page) 
(in English) multistability / CV / Fokker-Planck / Prefrontal Cortex / Working memory / Inhibitory / /  
Reference Info. IEICE Tech. Rep., vol. 106, no. 588, NC2006-127, pp. 55-60, March 2007.
Paper # NC2006-127 
Date of Issue 2007-03-07 (NC) 
ISSN Print edition: ISSN 0913-5685
Download PDF

Conference Information
Committee NC  
Conference Date 2007-03-14 - 2007-03-16 
Place (in Japanese) (See Japanese page) 
Place (in English) Tamagawa University 
Topics (in Japanese) (See Japanese page) 
Topics (in English) General 
Paper Information
Registration To NC 
Conference Code 2007-03-NC 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Inhibition-dominated network can explain multistability and highly irregular states in prefrontal cortex activity 
Sub Title (in English)  
Keyword(1) multistability  
Keyword(2) CV  
Keyword(3) Fokker-Planck  
Keyword(4) Prefrontal Cortex  
Keyword(5) Working memory  
Keyword(6) Inhibitory  
Keyword(7)  
Keyword(8)  
1st Author's Name Kosuke Hamaguchi  
1st Author's Affiliation RIKEN Brain Science Institute (RIKEN)
2nd Author's Name Nicolas Brunel  
2nd Author's Affiliation CNRS Universite-Rene Descartes (CNRS)
3rd Author's Name  
3rd Author's Affiliation ()
4th Author's Name  
4th Author's Affiliation ()
5th Author's Name  
5th Author's Affiliation ()
6th Author's Name  
6th Author's Affiliation ()
7th Author's Name  
7th Author's Affiliation ()
8th Author's Name  
8th Author's Affiliation ()
9th Author's Name  
9th Author's Affiliation ()
10th Author's Name  
10th Author's Affiliation ()
11th Author's Name  
11th Author's Affiliation ()
12th Author's Name  
12th Author's Affiliation ()
13th Author's Name  
13th Author's Affiliation ()
14th Author's Name  
14th Author's Affiliation ()
15th Author's Name  
15th Author's Affiliation ()
16th Author's Name  
16th Author's Affiliation ()
17th Author's Name  
17th Author's Affiliation ()
18th Author's Name  
18th Author's Affiliation ()
19th Author's Name  
19th Author's Affiliation ()
20th Author's Name  
20th Author's Affiliation ()
Speaker Author-1 
Date Time 2007-03-14 14:50:00 
Presentation Time 20 minutes 
Registration for NC 
Paper # NC2006-127 
Volume (vol) vol.106 
Number (no) no.588 
Page pp.55-60 
#Pages
Date of Issue 2007-03-07 (NC) 


[Return to Top Page]

[Return to IEICE Web Page]


The Institute of Electronics, Information and Communication Engineers (IEICE), Japan