IEICE Technical Committee Submission System
Conference Paper's Information
Online Proceedings
[Sign in]
... (for ESS/CS/ES/ISS)
Tech. Rep. Archives
... (for ES/CS)
 Go Top Page Go Previous   [Japanese] / [English] 

Paper Abstract and Keywords
Presentation 2008-09-26 10:00
Image analysis of higher-order nuclear architecture formed by a DNA recombinational repair protein RAD51
Akira Asano, Kazuteru Kono, Satoshi Tashiro (Hiroshima Univ.)
Abstract (in Japanese) (See Japanese page) 
(in English) It has been recently shown that the cell nucleus is a highly compartmentalized organelle with chromosome and chromatin domains formed by DNA. Although nuclear proteins also have been speculated to form higher order structure in the compartment between chromatin domains, how the formation of interchromatin compartment is organized is still unclear. We have previously shown that RAD51, a recombinational repair protein, forms nuclear foci, typically during S phase, and accumulates at sites of DNA double-strand breaks. We found that over-expressed RAD51 forms bundle-like structures in the nucleus. Since the structures are formed in the interchromatin compartment, we decided to study the influence of chromatin structure to the organization of interchromatin compartment. For this purpose, we examined the change of the RAD51 bundle-like structure shape after de-condensation of chromatin by the treatment with trichostatin A (TSA), a histone deacetylase inhibitor. The complexity of the GFP-RAD51 bundle-like structures was analyzed quantitatively using digital image processing methods.
Keyword (in Japanese) (See Japanese page) 
(in English) recombinatorial repair protein / chromatin structure / bioimaging / / / / /  
Reference Info. IEICE Tech. Rep., vol. 108, no. 213, SIP2008-97, pp. 43-46, Sept. 2008.
Paper # SIP2008-97 
Date of Issue 2008-09-18 (SIP, SIS) 
ISSN Print edition: ISSN 0913-5685  Online edition: ISSN 2432-6380

Conference Information
Committee SIS SIP IPSJ-AVM  
Conference Date 2008-09-25 - 2008-09-26 
Place (in Japanese) (See Japanese page) 
Place (in English) Tobata Campus, Kyushu Institute of Technology 
Topics (in Japanese) (See Japanese page) 
Topics (in English) Signal Processing, Intelligent Multimedia Systems, etc. 
Paper Information
Registration To SIP 
Conference Code 2008-09-SIS-SIP-AVM 
Language Japanese 
Title (in Japanese) (See Japanese page) 
Sub Title (in Japanese) (See Japanese page) 
Title (in English) Image analysis of higher-order nuclear architecture formed by a DNA recombinational repair protein RAD51 
Sub Title (in English)  
Keyword(1) recombinatorial repair protein  
Keyword(2) chromatin structure  
Keyword(3) bioimaging  
Keyword(4)  
Keyword(5)  
Keyword(6)  
Keyword(7)  
Keyword(8)  
1st Author's Name Akira Asano  
1st Author's Affiliation Hiroshima University (Hiroshima Univ.)
2nd Author's Name Kazuteru Kono  
2nd Author's Affiliation Hiroshima University (Hiroshima Univ.)
3rd Author's Name Satoshi Tashiro  
3rd Author's Affiliation Hiroshima University (Hiroshima Univ.)
4th Author's Name  
4th Author's Affiliation ()
5th Author's Name  
5th Author's Affiliation ()
6th Author's Name  
6th Author's Affiliation ()
7th Author's Name  
7th Author's Affiliation ()
8th Author's Name  
8th Author's Affiliation ()
9th Author's Name  
9th Author's Affiliation ()
10th Author's Name  
10th Author's Affiliation ()
11th Author's Name  
11th Author's Affiliation ()
12th Author's Name  
12th Author's Affiliation ()
13th Author's Name  
13th Author's Affiliation ()
14th Author's Name  
14th Author's Affiliation ()
15th Author's Name  
15th Author's Affiliation ()
16th Author's Name  
16th Author's Affiliation ()
17th Author's Name  
17th Author's Affiliation ()
18th Author's Name  
18th Author's Affiliation ()
19th Author's Name  
19th Author's Affiliation ()
20th Author's Name  
20th Author's Affiliation ()
Speaker
Date Time 2008-09-26 10:00:00 
Presentation Time 25 
Registration for SIP 
Paper # IEICE-SIP2008-97,IEICE-SIS2008-32 
Volume (vol) IEICE-108 
Number (no) no.213(SIP), no.214(SIS) 
Page pp.43-46 
#Pages IEICE-4 
Date of Issue IEICE-SIP-2008-09-18,IEICE-SIS-2008-09-18 


[Return to Top Page]

[Return to IEICE Web Page]


The Institute of Electronics, Information and Communication Engineers (IEICE), Japan