Paper Abstract and Keywords |
Presentation |
2018-01-27 13:10
Kaima Okubo, Yusuke Tsuruno, Takahiro Fujiwara, Umihiro Inoue, Yoshihisa Yamaoka, Eiji Takahashi (Saga Univ.) MBE2017-75 |
Abstract |
(in Japanese) |
(See Japanese page) |
(in English) |
To investigate the possibility that tumor cells migrate toward intratumor blood vessels according to the gradient of oxygen concentration in tissue, we devised the gap cover glass (GCG) that allows to produce gradients of oxygen in the monolayer cultured cells. To verify the oxygen gradients, we conducted oxygen imaging in the extracellular medium in cultured MDA-MB-231 and COS-7 cells using a ruthenium complex under conditions of different cell density, cell species, or cellular respiration, all of which significantly alter the oxygen consumption rate per unit volume of the cell. The measured oxygen gradients were consistent with the changes in the oxygen consumption rate. Thus, we conclude that the GCG produces gradients of oxygen in monolayer cultured cells. |
Keyword |
(in Japanese) |
(See Japanese page) |
(in English) |
tumor cells / oxygen gradients / migration / oxygen imaging / / / / |
Reference Info. |
IEICE Tech. Rep., vol. 117, no. 416, MBE2017-75, pp. 47-52, Jan. 2018. |
Paper # |
MBE2017-75 |
Date of Issue |
2018-01-19 (MBE) |
ISSN |
Print edition: ISSN 0913-5685 Online edition: ISSN 2432-6380 |
Copyright and reproduction |
All rights are reserved and no part of this publication may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopy, recording, or any information storage and retrieval system, without permission in writing from the publisher. Notwithstanding, instructors are permitted to photocopy isolated articles for noncommercial classroom use without fee. (License No.: 10GA0019/12GB0052/13GB0056/17GB0034/18GB0034) |
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MBE2017-75 |
Conference Information |
Committee |
MBE NC NLP |
Conference Date |
2018-01-26 - 2018-01-27 |
Place (in Japanese) |
(See Japanese page) |
Place (in English) |
Kyushu Institute of Technology |
Topics (in Japanese) |
(See Japanese page) |
Topics (in English) |
ME, generalImplementation of Neuro Computing,Analysis and Modeling of Human Science, |
Paper Information |
Registration To |
MBE |
Conference Code |
2018-01-MBE-NC-NLP |
Language |
Japanese without English title) |
Title (in Japanese) |
(See Japanese page) |
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Title (in English) |
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Keyword(1) |
tumor cells |
Keyword(2) |
oxygen gradients |
Keyword(3) |
migration |
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oxygen imaging |
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1st Author's Name |
Kaima Okubo |
1st Author's Affiliation |
Saga University (Saga Univ.) |
2nd Author's Name |
Yusuke Tsuruno |
2nd Author's Affiliation |
Saga University (Saga Univ.) |
3rd Author's Name |
Takahiro Fujiwara |
3rd Author's Affiliation |
Saga University (Saga Univ.) |
4th Author's Name |
Umihiro Inoue |
4th Author's Affiliation |
Saga University (Saga Univ.) |
5th Author's Name |
Yoshihisa Yamaoka |
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Saga University (Saga Univ.) |
6th Author's Name |
Eiji Takahashi |
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Saga University (Saga Univ.) |
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Speaker |
Author-1 |
Date Time |
2018-01-27 13:10:00 |
Presentation Time |
25 minutes |
Registration for |
MBE |
Paper # |
MBE2017-75 |
Volume (vol) |
vol.117 |
Number (no) |
no.416 |
Page |
pp.47-52 |
#Pages |
6 |
Date of Issue |
2018-01-19 (MBE) |
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